Abstract:Epidemiological studies indicate that the consumption of illegal substances is associated with a serious public health problem. To sum up, the present situation demands an immediate action, with major focus on reliable analytical methods which can be capable of detecting such compounds in biological fluids. Furthermore, the application of drug analysis in urine has increased significantly and for this reason, forensic toxicologists are being asked to determine and report their measurement uncertainty (MU) in drug analysis. The purpose of this study was to estimate the MU of confirmatory toxicological analysis of benzoylecgonine in urine by GC-MS. The limit of detection was 5.0 ng.ml -1 . The calibration curves were linear over the specified range (7.5 -3200 ng.ml
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