Ten years after the Human Genome Project, medicine is still waiting for many of the promised benefits, and experts have tempered their high expectations. Public opinion on genetic testing has generally been favourable but is this still the case? The aim of this study is to compare public experiences, beliefs and expectations concerning genetic testing over the years (2002 vs 2010). A cross-sectional questionnaire survey was conducted using the Dutch Health Care Consumer Panel in 2002 and 2010. Responses to questions in identical wording were compared. In 2002 and 2010, 817 (63%) and 978 (70%) members responded, respectively. Awareness and reported use of genetic tests remained stable over time. In 2010, more respondents expected genetic testing to become more widely applied, believed that knowledge about the genetic background of disease helps people live longer, and that testing should be promoted more intensively. In 2010, they were also more interested in their own genetic make-up. On the one hand, the concern that a dichotomy would emerge between people with 'good genes' and 'bad genes' was higher. On the other hand, respondents thought that insurance companies would be less likely to demand a genetic test in order to calculate health insurance premiums. In conclusion, the results suggest that in 8 years, expectations of benefits and potential use of genetic testing have been raised among the public, resulting in more positive opinions. Worries on inequity remain, although worries about premium differentiation by insurance companies have decreased.

Perceived risk and representations of cardiovascular disease (CVD), and preventive behaviour of people diagnosed with Familial Hypercholesterolemia by DNA testing (N = 81) were assessed. In general, participants perceived their own CVD risk as being relatively low. While participants reported almost optimal medication adherence (99%), only 49 per cent reported following recommendations concerning diet and physical activity. Family history of CVD was associated with both risk perception and the adoption of a healthy lifestyle. In their communications with FH-screened positives, health professionals should be aware that people may underestimate CVD risk, and should stress how behaviour change can reduce the risk.

The study investigated the relation between coping strategies of inmates and their psychological and physical well-being. General affective states such as optimism were related to both psychological and physical well-being. Moreover, inmates who experienced specific negative emotions such as regret, anxiety, and sadness reported more psychological and physical complaints. The way in which inmates coped with these negative emotions was also important. Inmates who used an active emotion-focused coping strategy were in better health than inmates inclined to keep their negative feelings to themselves. Emotion-focused coping by sharing negative emotions with people in one's social network can help to increase both psychological and physical well-being. Engaging in emotion management in a more cognitive way, by emphasizing positive aspects of the situation, can help to reduce the intensity of negative emotions. Possible research and policy implications of these results are discussed.

BackgroundA family history, reflecting genetic susceptibility as well as shared environmental and behavioral factors, is an important risk factor for common chronic multifactorial diseases such as cardiovascular diseases, type 2 diabetes and many cancers.DiscussionThe purpose of the present paper is to discuss the evidence for the use of family history as a tool for primary prevention of common chronic diseases, in particular for tailored interventions aimed at promoting healthy lifestyles. The following questions are addressed: (1) What is the value of family history information as a determinant of personal disease risk?; (2)How can family history information be used to motivate at-risk individuals to adopt and maintain healthy lifestyles in order to prevent disease?; and (3) What additional studies are needed to assess the potential value of family history information as a tool to promote a healthy lifestyle?SummaryIn addition to risk assessment, family history information can be used to personalize health messages, which are potentially more effective in promoting healthy lifestyles than standardized health messages. More research is needed on the evidence for the effectiveness of such a tool.

OBJECTIVE -To assess the potential effectiveness of communicating familial risk of diabetes on illness perceptions and self-reported behavioral outcomes.RESEARCH DESIGN AND METHODS -Individuals with a family history of diabetes were randomized to receive risk information based on familial and general risk factors (n ϭ 59) or general risk factors alone (n ϭ 59). Outcomes were assessed using questionnaires at baseline, 1 week, and 3 months.RESULTS -Compared with individuals receiving general risk information, those receiving familial risk information perceived heredity to be a more important cause of diabetes (P Ͻ 0.01) at 1-week follow-up, perceived greater control over preventing diabetes (P Ͻ 0.05), and reported having eaten more healthily (P ϭ 0.01) after 3 months. Behavioral intentions did not differ between the groups.CONCLUSIONS -Communicating familial risk increased personal control and, thus, did not result in fatalism. Although the intervention did not influence intentions to change behavior, there was some evidence to suggest it increases healthy behavior.