A supporting study was developed to identify the priority elements for conservation in the region called “Sierra de San Miguelito” (SSM), in the San Luis Potosi State (SLP), Mexico, with the purpose of establishing a federal protected natural area (PNA). The methodological approach used was the integral-spatial analysis applied in territorial planning processes. The study showed that the forests, xerophilous scrubland, and natural grasslands of the SSM present a high biodiversity, an abundance of endemism (27% of species are endemic to the country, n = 285), and protected species (5% of reported species). In addition, 32.74% of vertebrates and 18.32% of flora reported for SLP status is present in SSM, with an area that represents only 1.79% of the state territory. As a result of the study, an area of 109,638.95 ha was proposed to be declared a federally PNA. The area provides environmental services that favor the San Luis Potosí city (SLPc) and the surrounding population; therefore, its conservation will promote the preservation of natural, cultural, and landscape heritage, being a transversal axis for sustainable development in its area of influence. The result was the basis for starting the negotiation process, developed in 2021, for the creation of the PNA.
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