To overcome the effect of other components of complicated biological samples on nanopore stochatic sensing, displacement chemical reaction was utilized to selectively extract the target nucleic acid from whole blood. Given its simplicity and high sensitivity for detecting nucleic acids, our developed displacement chemistry-based nanopore sensing strategy offers the potential for fieldable / point-of-care diagnostic applications.
Traffic congestion wastes fuel and commuter's time and adds to CO2 emissions. Stop-and-go traffic instabilities can be suppresses using bilateral control-which differs from "car following" and adaptive cruise control in that, counter-intuitively, it uses information about the following vehicle (as well as about the leading vehicle). Stability can be proven mathematically [1], and can be demonstrated in simulation. A physical analog of a sequence of vehicles using bilateral control is a chain of masses connected by springs and dampers-a system which is inherently stable, since it lacks an external energy source. Here, in order to further understand bilateral control and its capacity to suppress instabilities, we move from a microscopic view (interaction of individual vehicles) to a macroscopic view (densities and flow rates). This leads us to the damped wave equation governing traffic under bilateral control. That equation allows us to determine the speed of propagation of disturbances, as well as their rate of decay. The equation is also useful in fine tuning parameters of bilateral control systems.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.