Abbreviations & Acronyms APA = aldosterone-producing adenoma ARR = aldosterone-to-renin ratio BP = blood pressure CI = confidence interval CT = computed tomography DBP = diastolic blood pressure PCR = polymerase chain reaction PHA = primary hyperaldosteronism SBP = systolic blood pressure SF-1 = steroidogenic factor-1 Objectives: The surgical cure rate of patients with aldosterone-producing adenoma varies widely, and causes of persistent hypertension are not completely established. The objective of this study was to assess the blood pressure outcome in patients after retroperitoneoscopic adrenalectomy, and to analyze the CYP11B2 344 C/T polymorphism and any factors associated with the outcome. Methods: Between 2002 and 2009, 82 patients with unilateral aldosterone-producing adenoma underwent retroperitoneoscopic adrenalectomy. Clinical and biochemical data were reviewed retrospectively. Patients were investigated to assess the association of the CYP11B2 344 C/T polymorphism with resistant hypertension after surgery. Results: Adrenalectomy cured hypertension in 44 patients (53.7%), and 27 patients (32.9%) had persistent hypertension that was much easier to control after surgery, whereas 11 patients (13.4%) had continued hypertension and poor blood pressure control. Multivariate regression analysis showed that the main determinants of postoperative cure were duration of hypertension less than 5 years (OR 4.515, 95% CI 1.978-10.293), number of antihypertensive medications Յ2 (OR 2.639, 95% CI 1.154-6.035), preoperative response to spironolactone (OR 3.105,) and the TT genotype of the CYP11B2 gene (344 C/T; OR 2.765, 95% CI 1.261-6.064). Correspondence Conclusions:The 344 C/T polymorphism of the CYP11B2 gene predicts resolution of hypertension in patients undergoing adrnelactomy for aldosterone-producing adenoma. Duration of hypertension, number of antihypertensive medications, and preoperative response to spironolactone also represents predictive factors that need to be considered for the identification of patients with continued postoperative hypertension requiring long-term monitoring and treatment.
A sequence planning algorithm based on multiple-constraint model was proposed to solve the problems in the bending process of complex workpiece. By employing a heuristic search based A* algorithm, the sequence planning was converted to a generalized shortest path problem, and then a multiple-constraint model which includes the factors of bending feasibility, dimensional accuracy and processing efficiency was introduced to optimize the search process. A bend sequence planning system has been realized based on this algorithm. The testing results of the system indicate that the algorithm is efficient and stability, and the planning time of complex bending workpiece was reduced effectively, especially for the workpieces which don’t have the valid bending process.
With main transmission system structural form of main servo motor-worm and worm gear commutation reducer-transmission screw-linkage force increasing mechanism, mathematical model of linkage force increasing mechanism is established to obtain the relationships of the velocity and displacement between nut and slide. Velocity and displacement of feature points of slide on the velocity-displacement curve inputted by user transform into which of nut by binary search algorithm and linear interpolation calculation. The feature points of nut transform into the velocity and displacement arrays of points based on S-curve, and then the arrays of points transfer through UDP protocol to lower computer. After the linear fine interpolation by Siemens Simotion D425 motion controller, slide moves according to the setting velocity-displacement curve. The experimental results show that slide moves smoothly, which meets specific technology requirements. The achievements have been successfully applied to a self-developed 2000KN mechanical linkage servo press in a production line of hot forming technology for more than one year, which extends the technology application scope of traditional mechanical press, and improves product quality.
BACKGROUND: Due to the influence of spinal and respiratory movements, it is difficult to accurately measure the range of motion of each joint. OBJECTIVE: To conduct a three-dimensional (3D) measurement of each joint in the shoulder complex in different postures in the sagittal plane of the upper extremity. METHODS: Thirteen healthy adults with no history of shoulder surgery for trauma or chronic pain were enrolled in the present study. The computed tomography (CT) imaging data of the shoulder complex were acquired in four postures via the reconstruction and alignment of 3D images. The angles of the postural changes were measured, and rotation vectors were used for descriptions and statistical analyses. RESULTS: There was a statistical difference in the rotation angles between the dominant and non-dominant sides of the sternoclavicular joint when the posture changed from a resting position to a posterior inferior position. During the postural change from a resting position to a horizontal position, the regression coefficient (β) of the humerothoracic joint to the sternoclavicular joint was 0.191, and the β of the humerothoracic joint to the glenohumeral joint was 0.621. During the postural change from the horizontal position to the rear upper position, the β of the humerothoracic joint to the sternoclavicular joint was 0.316, and the β of the humerothoracic joint to the glenohumeral joint was 0.845. During the postural change from the resting position to the rear lower position, the β of the humerothoracic joint to the glenohumeral joint was 0.991. CONCLUSION: The application of the image alignment technique enabled the direct and accurate measurement of the bony structures of the shoulder joint. The helical approach accurately described the scapulohumeral rhythm during 3D motion. There was a scapulohumeral rhythm of the shoulder complex during 3D composite sagittal movement, with different ratios for different joints and postures.
Currently, battery management system is one of the attraction research topics in the battery management technologies. This paper researches a battery management system based on RS232 and Ethernet, which provides the managers manage the remote batteries in the comfortable and large office. It greatly betters the workers working environment and lights the labor strength. Arm as the kernel of the management system, which is programmed by the real-time operate system uc/os. Through analyzing the requirement of the battery management, hardware system and software system are designed by the thought of layering. The layering thought builds the management system, which can be amended to adapt to the other management. It provides the flexible for the battery management system.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.