We report a case of granulomatous slack skin, a rare and indolent subtype of
mycosis fungoides. It affects mainly men between the third and fourth decades.
It is characterized by hardened and erithematous plaques that mainly affect
flexural areas and become pedunculated after some years. Histological
examination shows a dense infiltrate of small atypical lymphocytes involving the
dermis (and sometimes the subcutaneous tissue) associated with histiocytic and
multinucleated giant cells containing lymphocytes and elastic fibers
(lymphophagocytosis and elastophagocytosis, respectively). Patients affected by
this entity can develop secondary lymphomas. There are several but little
effective therapeutic modalities described. Despite the indolent behavior of
granulomatous slack skin, its early recognition and continuous monitoring by a
dermatologist becomes essential for its management and prevention of an
unfavorable outcome.
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