Overheating in buildings is one of the increasing concerns related to climate change and can lead to an increase in heat-related health issues and higher energy consumption due to the use of air conditioning systems. Literature shows that internal conditions and demand on environmental control systems can vary with height within buildings. However, an architectural trend towards highly glazed façades for tall buildings suggests the vertical gradient of performance is not always considered in the design process. By simulating a high-rise residential building in London, a comparative analysis of the overheating risks and daylighting at different levels in the building was conducted. In this study the model was able to consider the influence of surrounding built environment on solar gain and so influence of urban location on overheating risk was taken into account. Simulations were conducted using typical reference years as well as meteorological data for specific heat-wave periods experienced in London and that are expected to become more intense and frequent due to climate change. Passive mitigation options (external shading) are demonstrated to help reduce overheating occurrence by 74%, at the same time the impact of decreased daylighting (30%) is less problematic at higher levels where daylight factor is greater.