Findings
34Issues emerging from public participation activities include the role of the universal 35 right to health in Brazil, the balance between innovation and budget impact in
37England, the effect of unethical medical practices on public perception in South 38 39Korea, and the legitimacy of priority-setting processes in the USA. Providing 40 policymakers are receptive to these issues, public participation activities may be re-42 conceptualized as processes that illuminate policy problems relevant to a particular 43 44 context, thereby promoting an agenda-setting role for the public. The article offers an empirical analysis of public involvement in the case of 50 sofosbuvir, where the relevant considerations that bear on priority-setting decisions 52 have been particularly stark. The perspectives that emerge suggest that public 53 54 participation contributes to raising attention to issues that need to be addressed by 55 policy-makers. Public participation activities can thus contribute to setting policy 1 2 3 agendas, even if that is not their explicit purpose. However, the actualization of this 4 5 contribution is contingent on the receptiveness of policymakers. Hepatitis C, direct-acting antivirals (DAAs), sofosbuvir, public and patient 11 involvement (PPI), priority-setting, agenda-setting 12 13 14
15
Article Classification
16Case Study 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 59 attached to the disease (Vietri et al, 2013; Younossi and Henry, 2015). as much as $84,000 in the USA (McCarthy, 2015 Clinical and Economic Review (ICER).
8The article draws on country data on PPI and health priority-setting that was for PPI is also omitted for the purpose of this paper.
18In recent years a rapid development in treatments for chronic hepatitis C has administration were mostly through injections.
55However, at an estimated price of $84,000 for a 12-week treatment in the 56 USA, sofosbuvir has been labeled the $1,000 pill (McCarthy, 2015 Brazil's tradition of public involvement is also reflected in the way the public is
31In the case of sofosbuvir, the National Commission on Technology
33Incorporation in the National Health System (CONITEC), the HTA body in Brazil, contributions were made through submissions to the CONITEC website.
41During the process of assessing sofosbuvir, CONITEC also presented revised 42 43