Saliva plays an important role in oral health monitoring, regulating and maintaining the integrity of the oral hard tissues and some soft tissues. This paper reviews the role of saliva, the prevalence of oral dryness and the consequent importance of salivary flow as well as the relationship between xerostomia and salivary gland hypofunction amongst the causes of oral dryness. Other aspects of oral conditions associated with saliva are also reviewed including Sjögren's Syndrome and oesophageal function. Finally, knowledge, and the current use of salivary tests and the utilisation of saliva as a diagnostic fluid are surveyed.

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Xerostomia (dry mouth) is an uncomfortable and potentially harmful oral symptom which is usually caused by a decrease in the secretion rate of saliva (salivary gland hypofunction, or SGH). It is more prevalent in the elderly population, primarily due to their increased use of drugs and their susceptibility to disease. Many drugs and drug classes have been linked to xerostomia; the xerogenic effect increases when many drugs are taken concurrently. This Reference Guide to Drugs and Dry Mouth is designed to allow the reader to rapidly identify those pharmacologic agents which have the capacity to induce xerostomia and SGH. Xerogenic drugs can be found in 42 drug categories and 56 sub-categories. A guide to the management of drug-induced SGH and xerostomia is also provided.

Dry mouth (xerostomia) is a common complaint which occurs in about 25% of the elderly. Drugs play a principal role in its etiology. This REFERENCE GUIDE is designed to help the practitioner identify the medicaments which may cause this condition. Moreover, it offers suggestions for the treatment of drug‐induced dry mouth.

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This study was conducted to update our knowledge about the relation between sugar consumption and dental caries in nations throughout the world. Data on the prevalence of dental caries for 6- and 12-year-old children in, respectively, 23 and 47 nations were obtained from the World Health Organization's Global Oral Epidemiology Bank. Information on sugar supplies was obtained from Food Balance Sheet data prepared by the Food and Agriculture Organization of the United Nations. The study indicates that for the 12-, but not for the 6-, year-old-children there is a significant positive correlation between the per capita availability of sugar and dental caries. The data also suggest that the availability, and presumably the ingestion, of 50 g of sugar per day may represent an outer limit of "safe" or "acceptable" sugar consumption. Furthermore, a comparison of data obtained from Food Balance Sheets for the per capita daily "consumption" of sugar with data for consumption obtained from Household Consumption Surveys in six countries, shows that these data collection methods frequently do not give comparable results. Accurate, total, age-specific consumption figures with information on frequency and the manner of use are needed if the relationship between oral disease and dietary sugar is to be clarified.

Dry mouth is a common complaint among ambulatory diabetic patients. It is strongly associated with objective measurements of poor salivary flow and with other oral and extraoral symptoms of desiccation. The oral dryness is not associated with cardiovagal autonomic system dysfunction but may be due to disturbances in glycemic control.