The contamination of the aquatic environment with organic micropollutants, such as veterinary pharmaceuticals, has become an increasingly serious problem and has aroused attention in the course of the last decades. This study presents a screening for a series of veterinary antibiotics, potentially introduced by the application of liquid manure, in ground- and surface water of a drinking water catchment in Lower Saxony, Germany. Of the 26 compounds analyzed, eight, including sulfadiazine, sulfapyridine, sulfamethoxazole, trimethoprim, dehydrato-erythromycin, sulfadimidine, tylosin, and tetracycline were detected in surface water samples. Trimethoprim was detected in 11 out of 15 shallow groundwater samples, indicating its high environmental relevance. Column sorption experiments conducted on trimethoprim show a comparatively moderate sorption affinity to sandy aquifer material with a retardation coefficient of 5.7.

We revise gamma-ray limits on axion-like particles (ALPs) emitted from supernova SN1987A based on Solar Maximum Mission data. We improve and simplify the computation of the expected gamma-ray signal from ALP decays, while also extending it to non-instantaneous ALP emission. For the first time we make use of the temporal information in the data to update the associated ALP-photon coupling limits. For ALP decays, our updated likelihood only mildly affects the limit compared to previous works due to the absorption of gamma rays close to SN1987A. However, for ALP conversions in the Galactic magnetic field, temporal information improves the limit on the ALP-photon coupling by a factor of 1.4.

The increasing rates of preterm birth among twins implicate that solid data on associated risks and outcomes are required. Assessment of zygosity is often based on clinical criteria (evaluation of placenta; same gender, birth weight discordance as surrogate criteria for monochorionic/monozygotic twins). The aim of this study was to compare clinical versus genetic assessment of zygosity and to compare causes of preterm delivery as well as outcome data of very-low-birth-weight (VLBW; birth weight <1,500 g) twins stratified to zygosity. In a multicenter study, we selected n = 176 sets of same gender twins and determined zygosity genetically. In a subgroup of 123 sets of twins, the attending physicians at the study centers were asked to document the parameter 'zygosity' (monozygotic/dizygotic) on the basis of their clinical judgment. Concordance between genetic and clinical assessment was 62.7% for monozygotic twins and 88.9% for dizygotic twins, respectively. Outcome parameters (death, BPD, ROP, NEC, IVH) were comparable in both groups. Genetically dizygotic twins were significantly more often born due to intrauterine infection (33% vs. 20% in monozygotic twins, p < .01) and antenatal antibiotics were more frequently given to mothers of dizygotic twins (62% vs. 47% in monozygotic twins, p < .01). Obstetric complications such as twintwin-transfusion-syndrome were only seen in monozygotic twins as expected. The unexpected increase of antenatal antibiotic treatment and birth due to intrauterine infection in dizygotic twins should be confirmed in additional VLBW twin-cohorts.

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Modern work structures and organizations are often characterized by the simultaneous existence of multiple logics. Research has made profound efforts in describing a wide range of possible responses to different constellations of multiple logics in recent decades. But less is known about the subsequent effects of those responses. Since responses to multiple logics aim to change the initial constellation, they are likely to provoke counter-responses that alter the new constellation. Thus, as butterfly effect, certain strategies in dealing with multiple logics can initiate a series of responses that can lead to a fundamental change in the constellations of logics. The rise and fall of locum tenens physicians in Germany illustrate how series of responses can evolve, increase, and fundamentally alter the given constellation of logics. Thereby, our multi-method study also sheds light on the role of omnipresent actors and raises the question of how the actors can be theorized in a setting of multiple logics.