Accurate delineation of individual teeth and alveolar bones from dental cone-beam CT (CBCT) images is an essential step in digital dentistry for precision dental healthcare. In this paper, we present an AI system for efficient, precise, and fully automatic segmentation of real-patient CBCT images. Our AI system is evaluated on the largest dataset so far, i.e., using a dataset of 4,215 patients (with 4,938 CBCT scans) from 15 different centers. This fully automatic AI system achieves a segmentation accuracy comparable to experienced radiologists (e.g., 0.5% improvement in terms of average Dice similarity coefficient), while significant improvement in efficiency (i.e., 500 times faster). In addition, it consistently obtains accurate results on the challenging cases with variable dental abnormalities, with the average Dice scores of 91.5% and 93.0% for tooth and alveolar bone segmentation. These results demonstrate its potential as a powerful system to boost clinical workflows of digital dentistry.

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The molecular property–affinity relationships between flavonoids and xanthine oxidase were investigated through comparing binding constants obtained via fluorescence quenching measurements.

In this paper, we present an unsupervised framework for discovering, detecting, tracking, and reconstructing dense objects from a video sequence. The system simultaneously localizes a moving camera, and discovers a set of shape and appearance models for multiple objects, including the scene background. Each object model is represented by both a 2D and 3D level-set. This representation is used to improve detection, 2D-tracking, 3D-registration and importantly subsequent updates to the level-set itself. This single framework performs dense simultaneous localization and mapping as well as unsupervised object discovery. At each iteration portions of the scene that fail to track, such as bulk outliers on moving rigid bodies, are used to either seed models for new objects or to update models of known objects. For the latter, once an object is successfully tracked in 2D with aid from a 2D level-set segmentation, the level-set is updated and then used to aid registration and evolution of a 3D level-set that captures shape information. For a known object either learned by our system or introduced from a third-party library, our framework can detect similar appearances and geometries in the scene. The system is tested using single and multiple object data sets. Results demonstrate an improved method for discovering and reconstructing 2D and 3D object models, which aid tracking even under significant occlusion or rapid motion.

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Abstract-We present an unsupervised framework for simultaneous appearance-based object discovery, detection, tracking and reconstruction using RGBD cameras and a robot manipulator. The system performs dense 3D simultaneous localization and mapping concurrently with unsupervised object discovery. Putative objects that are spatially and visually coherent are manipulated by the robot to gain additional motion-cues. The robot uses appearance alone, followed by structure and motion cues, to jointly discover, verify, learn and improve models of objects. Induced motion segmentation reinforces learned models which are represented implicitly as 2D and 3D level sets to capture both shape and appearance. We compare three different approaches for appearance-based object discovery and find that a novel form of spatio-temporal super-pixels gives the highest quality candidate object models in terms of precision and recall. Live experiments with a Baxter robot demonstrate a holistic pipeline capable of automatic discovery, verification, detection, tracking and reconstruction of unknown objects.