PAGES 34687 AND 34688:Two figures contain minor errors. In panel A of Fig. 2, the terms spliced and unspliced are reversed. The chemical structure shown in panel A of Fig. 3 should include two additional methyl groups attached to the ring at the right hand side of the molecule. This structure is shown correctly in supplemental Table 2 (A9). These corrections do not affect the interpretation of the results or conclusions of this work.
We present BurstCube, a novel CubeSat that will detect and localize Gamma-ray Bursts (GRBs). BurstCube will detect long GRBs, attributed to the collapse of massive stars, short GRBs (sGRBs), resulting from binary neutron star mergers, as well as other gamma-ray transients in the energy range 10-1000 keV. sGRBs are of particular interest because they are predicted to be the counterparts of gravitational wave (GW) sources soon to be detectable by LIGO/Virgo. BurstCube contains 4 CsI scintillators coupled with arrays of compact low-power Silicon photomultipliers (SiPMs) on a 6U Dellingr bus, a flagship modular platform that is easily modifiable for a variety of 6U CubeSat architectures. BurstCube will complement existing facilities such as Swift and Fermi in the short term, and provide a means for GRB detection, localization, and characterization in the interim time before the next generation future gamma-ray mission flies, as well as space-qualify SiPMs and test technologies for future use on larger gamma-ray missions. The ultimate configuration of BurstCube is to have a set of ∼ 10 BurstCubes to provide all-sky coverage to GRBs for substantially lower cost than a full-scale mission.
Continuous hydrogenation using ACMC-Pd
monolith catalysts was studied
for four chemistries of industrial interest. The chemistry was run
in a 30.5 cm catalyst bed with repeated passes to simulate a longer
commercial catalyst bed in which >97% conversion would be completed
in a single pass of the reactor with no recycle. The selected liquid
flow rate (0.086 cm/s) enabled >97% conversion for the four chemistries
using practical ranges of temperature (60–180 °C), pressure
(0.348 to 3.48 MPa), and required bed lengths (4.3 to 6.1 m). The
unsaturated bonds hydrogenated included nitro, carbonyl, olefin, and
aromatic bond types. The most challenging reaction was the conversion
of a neat olefinic/aromatic substrate (requiring 7 moles of hydrogen
per mole of product) run with a low-temperature/high-temperature reactor
configuration. The same catalyst was used for all of the chemistries,
and the changeover from one chemistry to another involved simple solvent/substrate
rinses of the reactor. The data can be used to estimate the number
of commercial reactor tubes, temperature, pressure, and bed length
needed for the production of commercial quantities of specialty and
pharmaceutical chemicals.
The intervention was associated with an increased number of 25-OH vitamin D assays and DXA scans but not with more prescriptions for bone protective therapy. This suggests that a public health education campaign and provision of a 'prompt' for GPs was only partially successful at improving OSP management post-MTF. This has driven establishment of a Fracture Liaison Service.
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