Objective: This study aimed to valorize two medicinal plants used against Loa loa filarial in Gabon. Material and Methods: Powders of leaves of Senna occidentalis and stems and leaves of Cissus quadrangularis were proposal to successive extractions by solvents with increasing polarities (cyclohexan, dichloromethan, methanol and demineralized water). Qualitative Phytochemistry screening was established using the standard color and/or precipitation reactions. Results: The results reveal the predominance of total sugar, alkaloids, and phenols in all extracts. Cathechic tannins, reducing sugar, and flavonoids on many extracts were tested. Gallic tannins and coumarins are found in some extracts. They are very few quinones, triterpenes or sterols in the two species. Conclusion: Some secondary metabolites have proved filaricide activities already. The abundance of chemical compounds present in these medicinal plants would justify their usage. However, the evaluation of biological activities on the Loa loa filarial along with toxicity remains unexplored.
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