Several constructs reflecting individual differences in emotion expression have been described in the literature, yet their structural organization is unknown. The present study provided a taxonomy of these individual differences and determined their relations to depression and anxiety symptoms. exploratory factor analyses suggested seven emotion-expression factors-affect intensity, ambivalence about expression, disclosure of Negative emotion, disclosure of emotion, disclosure of Lack of affect, expression of Positive emotion, and Secret Keepingare explained by two second-order factors: emotional Constraint and emotional expression. Multiple regression and canonical correlation analyses suggested that a reluctance to express emotions is related to heightened psychological symptoms. These findings bridge constructs from disparate literatures, and they provide support for emotion dysregulation models of affective disorders. In the past couple of decades there has been an upsurge of research on individual differences related to the expression of emotion. Advances in theories of emotion regulation (Gross, 1998a, 1998b) and the health benefits of disclosure (Kennedy-Moore & Watson, 2001;
Intimate partner violence (IPV) costs women nearly 8 million days of paid work annually. Greater attention to violence survivors' employment and career development can facilitate women escaping abusive relationships and promotes their overall rehabilitation and healing. A first step to increasing attention to survivors' career development includes collaborating with social service agencies in an effort to translate career intervention research findings into community-based practice. The purpose of this article is to provide a description of an individual career counseling model that the authors use to serve women IPV survivors. The authors review the structure of the service model, the theoretical and research foundations, and describe two case examples to highlight career counseling interventions relevant for women survivors.
To define and therapeutically target mechanisms that mediate nasopharyngeal carcinoma (NPC) metastasis, we have developed a unique orthotopic xenograft mouse model that accurately recapitulates the invasive and metastatic behavior of human disease. Based on clinical and laboratory evidence that the PI3K/Akt/mTOR axis is involved in aggressive NPC tumor behavior, we chose it as a therapeutic target to test the utility of our orthotopic system for evaluating the effectiveness of a targeted treatment for metastatic NPC. Demonstrated herein, we have shown that both the development and growth of metastatic lesions are markedly reduced by the mTOR inhibitor sirolimus. Thus, this orthotopic model provides a platform to study potential therapeutics for advanced NPC and demonstrates that targeting the PI3K/Akt/mTOR pathway is a promising intervention against disseminated disease.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.