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For a successful transformation towards a sustainable bioeconomy, cooperative knowledge creation leading to innovations through research at the company and academic level are important. Urban regions are the centre of economic and research activities. The example of the region of Stuttgart, which aims to complement its mature industrial structure with new opportunities related to the knowledge-based bioeconomy, is an interesting case for the application of social network analysis to shed light on the dynamics of innovation networks to support the transformation of urban regions. As with smaller spatial levels of observation connectivity in network decreases, we find a scale-free network structure for the supra-regional network and a star-like network structure for the regional network, with two universities and one transfer-oriented research institutes at the core. While research collaborations beyond regional borders and across different industries foster knowledge co-creation, the central actors can be recognized as gatekeepers who dominantly influence knowledge flows. To potentially strengthen the resilience of the network, policy and industry associations serving as network facilitators can foster collaboration between periphery actors. The case of the Stuttgart region impressively illustrates the opportunities of the knowledge-based bioeconomy for urban regions and the complementary role traditional manufacturing sectors can take in the transformation towards higher degrees of sustainability.

Concerns about sustainability challenges are growing. Companies are under pressure to rethink existing innovation paradigms. In this context, research interest in the resource-constrained innovation concept, frugal innovation, has increased. In this paper, we examine the impact of frugal innovation on the economic, social, and ecological sustainability dimensions by conducting a systematic literature review of 44 papers. We find that frugal innovation is a promising approach to promote sustainable development from an economic perspective and a social perspective. Nevertheless, positive and negative effects exist in all three dimensions. Thus, a positive relationship is not inherent but must be proactively formed. External factors can influence the impact of frugal innovation on sustainability. For future research we recommend (1) establishing a unified understanding of frugal innovation through a clear definition, (2) broadening the research focus to a global perspective, (3) assessing the impact of frugal innovation along the entire product life cycle, and (4) investigating characteristics that make frugal innovation sustainable.