Summary The blood flow in 71 Patients and methods Doppler studySixty-seven patients with 71 primary untreated skin melanomas were examined by a 10MHz continuous wave Doppler ultrasound flowmeter before biopsy. The flowmeter was used with a Park's pencil probe of 0.5cm diameter (Park's Inc., USA). The probe was applied over the lesion with ultrasound coupling gel. To avoid any pressure over the lesion the probe was placed 2-3mm away from the tumour, lying embedded in the gel. Dry keratotic lesions were moistened with water before applying the gel. A lesion was called Doppler flow positive if pulsatile audible signals were detected with the probe lying at a tangential plane to the skin surface. In the case of flat macular lesions the probe was put horizontally on the skin surface with its tip being about 4-mm away from the margin of lesion and then pressed gently pointing its tip towards the lesion. If no flow signals were detected at the tangential plane the tumour was called Doppler flow negative. On detection of flow signals, the probe angle was altered to obtain a maximum amplitude (systolic peak) signal on the Angioscan spectrum analyser (Unigon Inc., USA). These signals were then recorded on an audio stereo cassette recorder (AKAI-HX-3; AKAI Electric Company Ltd, Japan Figure 1).
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