Nephrotic Syndrome (NS) is a common childhood illness characterized by massive proteinuria, hyperlipidemia, hypoalbuminemia & edema. NS is a disease of relapse and it is a major problem to manage the cases with frequent relapse. So it is very important to find out such children who are prone to develop frequent relapse. This retrospective study was conducted in the paediatric department of Dhaka Medical College Hospital (DMCH) from January to December 2005.Total 100 children with relapsed NS of them 50 had Frequent Relapse NS (FRNS) and 50 had Infrequent Relapse NS (IFRNS) were included in the study with a view to find out the risk factors for relapse. Data were collected from previous medical and hospital records. Data were analyzed by using SPSS program. Chi-squared test and Student's t-Test were used as statistical test and p value < 0.05 was taken as significant. NS was more common among 2-6 years of age (67%) with male to female ratio roughly 2:1. Most of patient with frequent relapse had age <5 years, came from rural area and belongs to poor social class compared to that of infrequent relapse. The mean age at first onset was significantly less in frequent relapse group than that of infrequent relapse group. Majority of atopic child belongs to frequent relapse cases. Low serum albumin level, low serum total protein level, culture positive Urinary Tract Infection (UTI) at initial attack were observed to be statistically significant in case of frequent relapse group.DOI: http://dx.doi.org/10.3329/fmcj.v7i1.10292Faridpur Med. Coll. J. 2012;7(1): 18-22

Objectives: The objective of this study was to observe the outcome of patients treated with penicillamine. Design: Intervention type of study Setting: Department of Paediatrics, Dhaka Medical College Hospital Study period: January 2007 to December 2008. Study subjects: Sixteen diagnosed cases of Wilson's disease as per inclusion criteria. Intervention: D-penicillamine was started in a low dose, which was titrated gradually. The clinical and biochemical parameters were evaluated to look for the response to treatment. Results: A total of 16 cases were included. Among them 12 were male and 4 were female. The mean (± SD) of age of the patients was 10 (± 2.34) years. Consanguinity between parents was present in 44% (n=7). The hepatic and neurological variety of WD were 56 % (n=9) and 44% (n=7) respectively. The K-F ring was present in 75% (n=12/16) of WD cases. The excretion of 24 hrs urinary copper was steadily increased from discharge till second follow-up in response with increasing dose of penicillamine, thereafter the value was declining gradually till final follow-up at 1 year. Regarding outcome, 7 patients improved of which 4 were in hepatic and 3 in neurological group, 3 of hepatic WD expired and 2 developed neurological manifestations. One patients developed proteinuria while penicillamine treatment .About half of patients with WD were improved. Adequate cupriuresis occurred at three months. All the symptoms and biochemical markers WD improved gradually. No significant side effect was seen. Key words: Wilson's disease; penicillamine; urinary copper. DOI: 10.3329/jdmc.v18i1.6304 J Dhaka Med Coll. 2009; 18(1) : 37-43

DOI: http://dx.doi.org/10.3329/jdmc.v20i2.10549 J. Dhaka Med. Coll. 2011; 20(2): 193-198

Background: Skeletal manifestations associated with ALL in children are common findings with a high prevalence (11.6 to 50%). The most common skeletal manifestations are bone pain, arthritis, failure to use an extremity as well as other complaints mimicking orthopedic condition such as osteomyelitis. The objective of this study is to determine the rate of skeletal manifestations commonly present in ALL to reduce mortality and morbidity. Methods: This cross-sectional study was carried out in the department of Pediatrics in Dhaka medical college Hospital, BSMMU and Dhaka Shishu (Children) Hospital between January 2010 to July 2010. Total Fifty patients of ALL were Selected consecutively from the study population. At first, we assessed skeletal manifestations like bone pain, arthritis, radiological findings present or not in ALL. Then specify the rate of bone pain, arthritis, radiological findings of ALL patients. Results: After six months 35 patients were present with skeletal manifestations. Among them 20 patients, presented with bone pain,10 patients presented with arthritis and 5 patients presented with radiological manifestations. Out of 5 patients 3 patients had soft tissue swelling 1 patient had periarticular osteoporosis and 1 patient had joint effusion in x-ray findings. Conclusion: Skeletal manifestations may be the only presentation in ALL. Bangladesh J Child Health 2019; VOL 43 (2) :102-105

not availableBangladesh J Child Health 2015; VOL 39 (2) :99-101