Background: Acne is an inflammatory disease of the hair follicles. There are many treatments from medication to non-medication in which antibiotics are a widely used and effective group. However, the recent overuse of antibiotics has led to an increase in resistance to drugs by P. acnes. Therefore, this study is extremely necessary. Objectives: To determine the antibiotic resistance rate and a number of factors related to Propionibacterium acnes antibiotic resistance rate in acne patients at Can Tho Hospital of Dermato-Venereology. Materials and methods: the cross-sectional descriptive study was carried out on of 43 acne patients at Can Tho Hospital of Dermato-Venereology. Results: resistance rates for antibiotics were cefuroxime (91.7%), ceftriaxone (87.5%), cefotaxime (87.5%), trimethoprim (85.4%), clindamycin (66.7%), ofloxacin (41.7%), ciprofloxacin (25%), levofloxacin (20.8%), tetracycline (16.7%). All patients participating in the study were resistant to at least 2 or more antibiotics of which the highest resistance level was 6 antibiotics (37.5%). Some related factors such as the history of antibiotic treatment accounted for 35.4%. Severity levels were classified into mild acne 60.1%, average 27.1% and severity 12.5%; there were two clinical forms in our study including acne vulgaris (77.1%) and cystic acne (22.9%). However, when examining the relationship between these factors and antibiotic resistance, this difference is not statistically significant. Conclusion: P. acnes are increasingly resistant to many antibiotics, making treatment more difficult, a number of factors related to this condition for example antibiotic use, level of severity of acne.
Background: Atopic dermatitis is a common skin disease in children as well as in adults, with the important feature of being recurrent. Immune disorders (the role of Specific IgE serum) have a relation to the severity of the disease and the risk of allergy in patients. Objectives: 1). To describe the clinical features of patients with atopic dermatitis at Can Tho Hospital of DermatoVenereology in 2021; 2). To determine the total and specific IgE serum concentration in patients with atopic dermatitis at Can Tho Hospital of Dermato-Venereology in 2021. Materials and methods: A cross-sectional descriptive study was carried out on 50 patients with atopic dermatitis hospitalized at Can Tho Hospital of Dermato-Venereology. Results: The rate of itching and types of eczematous lesions accounted for 100%, skin lesions with typical morphology and age-specific patterns were approximately 92%, chronic or relapsing history held 80%, xerosis rate was up to 82%, early age of onset made up 18%, the rate of increase in total and specific IgE serum level in patients with atopic dermatitis was 54% and 84%, respectively, the mean total IgE serum concentration was 210.01 ± 157.88 IU/mL, the lowest was 6.54 IU/mL and the highest was 741.23 IU/mL. D. pteronyssinus and D. farina accounted for the highest proportion of respiratory allergens (46%), cocoa beans accounted for the highest proportion of food allergens (28%). Conclusions: Atopic dermatitis in adult patients associated with pruritus, D. pteronyssinus and D. farina in respiratory allergens and cocoa beans in food allergens was the most common. Total and specific serum IgE concentrations are often elevated in patients with atopic dermatitis.
Background: Syphilis is a chronic infectious disease caused by Treponema pallidum. Classically, syphilis is classified into 4 stages including primary, secondary, latent and tertiary syphilis. Many of its manifestations are cutaneous, making it of interest and importance to dermatologists, especially as morbidity from syphilis rises in the developed world and continues in the developing world. Objectives: 1). To describe the clinical characteristics of secondary syphilis patients at Can Tho Hospital of Dermato-Venereology in 2021; 2). Todescribe the serological characteristics of secondary syphilis patients at Can Tho Hospital of Dermato-Venereology in 2021. Materials and methods: A cross-sectional descriptive study was carried out on 52 secondary syphilis patients who were treated at Can Tho Hospital of Dermato-Venereology. Results: Lesions of macules, papules, pustules, scales, mucous patches were 73.1%, 55.8%, 0%, 23.1%, 11.5%, 7.7%, respectively. The highest percentage of sites was on the palms and/or soles with 86.5%. Serum RPR titer had the highest rate was R256, accounting for 57.7%, most of the patients had serum TPHA titer of R1280, accounting for 73.8%. Conclusions: Secondary syphilis patients have a variety of clinical manifestations and affected sites, most of serum PRP and TPHA titers are usually high with values of R256 and R1280, respectively.
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