A family is reported with central cloudy dystrophy of the cornea, as described by Frangois in 1956. The lesion consists of a grey zone deep in the stroma, made up of polygonal or rounded areas with indistinct margins, separated by apparently clear, normal stroma. No deposits are visible in the slit lamp. The anterior and posterior boundary layers appear normal. The corneal thickness is normal. Open angle glaucoma was present in the family. The pathogenesis of the dystrophy is unknown, and histopathological examination has not been described. The differential diagnosis is briefly discussed. The family tree is suggestive of a dominant mode of transmission.In 1956 Fransois described a corneal dystrophy, visible only with the slit lamp, affecting the deep (posterior) layers of the central stroma. The lesion consisted of cloudy grey areas with indefinite structure and indistinct margins. The endothelium and epithelium were unaffected. Frangois described eight cases, ranging in age from 35 to 76 years, two were members of a sibship of five, while the remaining six cases were sporadic. The visual acuity was not affected.
A retrospective evaluation of the results obtained with primary implantation of an iris clip lens, performed in four Danish eye departments, is given. Altogether 203 implants were carried out. The mean age of the patients at the time of operation was 77 years. Seventeen patients had bilateral implantation. Besides the cataract, the age of the patients was main indication for implantation. Contributing indications were monolateral cataract, macular degeneration, and general somatic or psychic incapacity. The incidence of more serious complications was (more than one complication in some eyes): corneal dystrophy 13/203, deposits on the clip lens or in the pupil 18/203, secondary glaucoma 2/203, macular oedema 2/203, late recurrent hyphaema 2/203 and dislocation of the clip lens 6/203. Seven clip lenses were removed. A corrected visual acuity of 6/12 or above was found in 56% of the cases postoperatively. In spite of the complications it is considered justifiable to continue with clip lens implantation in elderly patients, to solve the optical problems following aphakia.
In a preliminary communication, V . A . /ensen and K . Lundbcek (1968) described the fluorescence-angiographic picture of the iris and reported that leakage of fluorescein was seen at the pupillary border in long-term diabetics. These studies were done with a Zeiss fundus-camera.The present work reports fluorescence-angiographic iris studies in a larger group of both diabetics and non-diabetics. MethodThe studies were performed using a Zeiss Photo-slit-lamp modified by /. Bruun-/ensen. With this equipment it is possible to take a series of pictures of the iris, or any other part of the anterior segment of the eye, in rapid succession.The reason why the photo-slit-lamp was used instead of the fundus camera was that it was thereby possible to displace the lighthreflex produced by the incomming light towards the periphery of the cornea so that it did not mask the fluorescence angiographic changes at the pupillary border.
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