Highlights
Malian healthcare workers presented mental disorders in the early stage of COVID-19.
Nurses were at lower risk of mental health disorders than other worker categories.
Women were at greater risk of mental health disorders than men.
A lack of protection equipment and nurses was associated with mental disorders.
ObjectivesTo document patients’ and healthcare professionals’ (HCP) experiences with hepatitis B virus (HBV) and hepatitis C virus (HCV) diagnosis and care, as well as consequences of these infections on patients’ life trajectories in Cameroon, an endemic country in sub-Saharan Africa.DesignQualitative sociological study combining in-depth interviews and observations of medical consultations. Interviews and observations transcripts were thematically analysed according to the following themes: circumstances and perceptions surrounding hepatitis screening, counselling and disclosure, information provided by HCP on hepatitis prevention and treatment, experience of access to care and treatment, social/economic trajectories after diagnosis.SettingHIV and gastroenterology/medical services in two reference public hospitals in Yaoundé (Cameroon).Participants12 patients affected by HBV and/or HCV (co-infected or not with HIV), 14 HCP, 14 state and international stakeholders.FindingsMany patients are screened for HBV and HCV at a time of great emotional and economic vulnerability. The information and counselling delivered after diagnosis is limited and patients report feeling alone, distressed and unprepared to cope with their infection. After screening positive, patients struggle with out-of-pocket expenditures related to the large number of tests prescribed by physicians to assess disease stage and to decide whether treatment is needed. These costs are so exorbitant that many decide against clinical and biological follow-up. For those who do pay, the consequences on their social and economic life trajectories are catastrophic.ConclusionLarge out-of-pocket expenditures related to biological follow-up and treatment pose a real challenge to receiving appropriate care. Free or reasonably priced access to hepatitis B and C treatments can only be effective and efficient at reducing the hepatitis disease burden if the screening algorithm and the whole pretherapeutic assessment package are simplified, standardised and subsidised by comprehensive national policies orientated towards universal healthcare.
Background:
Intimate partner violence in its various forms increases HIV exposure in
female victims and potentially jeopardizes the HIV treatment cascade, for
instance, by impeding engagement in and adherence to care. Elevated rates of
HIV and intimate partner violence are reported in Central Africa. Evidence
on the effect of intimate partner violence on antiviral therapy interruption
is lacking in Cameroon, where only 330,000 women live with HIV and only 19%
of HIV-positive people are virally suppressed. This study aimed to assess
the prevalence and factors of intimate partner violence against HIV-positive
women and its relationship with antiretroviral therapy interruption
⩾1 month.
Methods:
The EVOLCam cross-sectional survey was conducted in 19 hospitals in the
Center and Littoral regions. The study sample comprised antiviral
therapy–treated women declaring at least one sexual partner in the previous
year. Scores of recent emotional, physical, extreme physical and sexual
intimate partner violence were built using principal component analysis and
categorized under no, occasional or frequent intimate partner violence.
Multivariate logistic analyses were performed to investigate the
relationship between intimate partner violence and recent antiretroviral
therapy interruption ⩾1 month, and associated factors.
Results:
Among the 894 analyzed women, the prevalence of intimate partner violence was
29% (emotional), 22% (physical), 13% (extreme physical) and 18% (sexual).
Frequent physical intimate partner violence was a significant risk factor of
antiretroviral therapy interruption ⩾1 month (adjusted odds ratio = 2.42
(95% confidence interval = 1.00; 5.87)). It was also associated with
HIV-related stigma (2.53 (1.58; 4.02)), living with a main partner (2.03
(1.20; 3.44) and non-defensive violence against this partner (5.75 (3.53;
9.36)).
Conclusion:
Intimate partner violence is a potential barrier to antiviral therapy
continuity and aggravates vulnerability of Cameroonian HIV-positive women.
The prevention and detection of intimate partner violence by HIV services
might help to reach the last “90” of the 90-90-90 targets.
Besides identifying individual factors of TI>2d, our study highlighted the role of health care supply-related factors in shaping TI in Cameroon's ART programme, especially the deleterious effect of ART stock-outs. Our results also suggest that the high proportion of patients reporting TI could jeopardise progress in the fight against HIV in the country, unless effective measures are quickly implemented like ensuring the continuity of ART supply.
Objectives
In terms of HIV infection, western and central Africa is the second most affected region world‐wide, and the gap between the regional figures for the testing and treatment cascade and the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90–90–90 targets is particularly worrying. We assessed the prevalence of virological suppression in patients routinely treated in 19 hospitals in Cameroon.
Methods
A cross‐sectional survey was performed in adult patients receiving antiretroviral therapy (ART) in the Centre and Littoral regions. The prevalences of virological suppression (<1000 HIV‐1 RNA copies/mL) were compared among all 19 hospitals using the χ2 test. Potential individual and health care‐related determinants of virological suppression were assessed using multivariate logistic regression models.
Results
A total of 1700 patients (74% women; median age 41 years; median time on ART 3.7 years) were included in the study. The prevalence of virological suppression was 82.4% overall (95% confidence interval 80.5–84.2%). It ranged from 57.1 to 97.4% according to the individual hospital (P < 0.001). After adjustment, virological suppression was associated with age, CD4 cell count at ART initiation, disclosure of HIV status to family members, interruption of ART for more than two consecutive days, and location of patient's residence and hospital (rural/urban). These factors did not explain the heterogeneity of virological suppression between the study hospitals (P < 0.001).
Conclusions
The overall prevalence of virological suppression was reassuring. Nevertheless, the heterogeneity of virological suppression among hospitals highlights that, in addition to programme‐level data, health facility‐level data are crucial in order to tailor the national AIDS programme's interventions with a view to achieving the third UNAIDS 90 target.
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