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S28In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer R. Rudalska et al. S37Machine learning algorithms outperform conventional regression models in predicting development of hepatocellular carcinoma A. G. Singal et al.

The secrets of healing without scars Potential treatments for burns and wounds S89 ENVIRONMENT When the first defence fails Skin absorbs more pollutants than expected S91 MICROBIOME Community effort Do microbes on skin protect or pose a threat? S94 NUTRITION Edible skin care How certain diets could benefit skin S96 ELECTRONICS Beyond the biological Incorporating a sense of touch into prostheses S99 PERSPECTIVE The eye of the beholder Consider the needs of all members of the vitiligo community, says John Harris

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Calling cells to arms Different strategies for immunotherapy S4 BACTERIOLOGY A caring culture Century-old approach brings new hope S6 DRUG DEVELOPMENT Releasing the brakes Unleashing the immune system to fight cancer S9 Q&A Evidence presenter Karolina Palucka explains how dendritic cell vaccines can target tumours S10 MEDICAL IMAGING Removing the blindfold Video captures tumour-immune interactions S13 ADAPTIVE CELL THERAPY Honing that killer instinct Engineering a better immune response S16 CANCER VACCINES Material breach Plastic fantastic for implantable vaccines

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