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declare that they have no conflict of interest.Ethics approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.Informed consent: Informed consent was obtained from all individual participants included in the study.Data availability: The datasets generated and analyzed during the current study are available from the corresponding author on reasonable request.Code availability: The model code that we developed is provided as an electronic supplementary information, so the model can be copy-pasted by any reader and run directly on Monolix® software with the users' own dataset.

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