Background: Epilepsy is a condition characterized by recurrent seizures that occur due to the disruption of brain function caused by an abnormal electrical charge on brain neurons. Epilepsy has two categories of seizures, they are focal seizures and generalized seizures. The incidence of epilepsy is estimated to be more prevalent in developing countries than developed countries. In 2017, the number of cases of children with epilepsy in West Sumatra, especially at RSUP Dr. M. Djamil Padang, there are 1081 cases in the outpatient and inpatient cases and will be expected to increase every year.Purpose: To find out the characteristics of epilepsy disease in the children's ward RSUP Dr. M. Djamil Padang in 2018.Method: This research was conducted at RSUP Dr. M. Djamil Padang. This research is descriptive with cross sectional design. Data sources from secondary data derived from medical records. Samples were selected using inclusion and exclusion criteria. Data analysis uses univariate analysis.Results: The results of the study were obtained from 65 samples suffering from epilepsy, there are age 0-5 years as many as 37 people (56.9%), male gender as many as 39 people (60%), do not have a family history of epilepsy as much as 62 people (95.4%), picture of sharp wave and spikes EEG as many as 30 people (46.2%), generalized seizure type as many as 57 people (87.7%) and valproic acid as one of the management of epilepsy as many as 32 people (49, 2%).Conclusion: From the results of this study, it can be concluded that most people with epilepsy are aged 0-5 years with male sex and do not have a family history of epilepsy. The types of EEG images are sharp waves and spikes, the type of generalized seizures with the most management of valproic acid.
Tuberculosis in children is still a challenge for world health problems, especially in establishing a diagnosis. Under diagnosis or over diagnosis can occur in some cases, so getting accurate data is still a challenging task. Clinical symptoms that are not typical in children add to the difficulty of diagnosis enforcement, especially in areas with a high incidence of TB infection. There has been much development of diagnostic TB methods in children, including genetic approach. Some studies report that miRNAs play an essential role in tuberculosis pathogenesis. MicroRNA as one of the diagnostic genetic methods can distinguish the incidence of latent and active infection in tuberculosis cases in children.
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