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SUMMARY BackgroundIrritable bowel syndrome (IBS) is a common, chronic disorder that reduces patients' quality-of-life. Although highly prevalent, little is known about patients' understanding of this disorder.

Background & Aims-Recent studies of C. difficile infection (CDI) indicate a dramatic increase in metronidazole failure. The aims of this study were to compare current and historical rates of metronidazole failure and identify risk factors for metronidazole failure.

The survey instrument was found to be reliable, valid and usable. It provides descriptive data on patient knowledge, fears, and concerns surrounding irritable bowel syndrome. This easily administered questionnaire should provide novel information to improve patient care.