Drug use has been associated with craving, which may be described as a powerful and sometimes overwhelming urge to use the drug. Patients seeking treatment for methylamphetamine dependence must cope with drug cravings as they engage in psychosocial treatments. Changes in brain GABA(A) receptors during substance use and withdrawal provide a neurobiological basis for craving and associated anxiety. Flumazenil (a benzodiazepine antagonist) plus gabapentin (an antiepileptic) were compared with placebo in a randomized, double-blind study to assess the effects on craving during initial treatment for methylamphetamine dependence. Evaluation was conducted over a 30-day period. Craving and drug use were found to be highly correlated. Craving was reduced significantly in the flumazenil plus gabapentin group compared with placebo following the initial treatment period and throughout the 30 days. Decreased methylamphetamine use was also observed, as measured by urine drug screens and self-reports.

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The present paper deals with how pre-intervention data were gathered from a sample of junior high school students to whom a smoking prevention program was addressed and how these data were used in the creation of trigger films which were an important element in the prevention program. The coping techniques used by students who are successfully able to withstand social pressures to smoke were determined from pre-intervention group interview-role-playing sessions with samples of students from two schools representative of the intended target population of the smoking prevention program. These data were used in the production and editing of ten-minute, sound, color films which reflected simulations of the student responses in the interview-role-playing sessions. Assessment of the impact of these filmed social-inoculation coping strategies indicates that they appear to be a promising component of smoking deterrent programs for adolescents.

The present study investigated informed consent procedures as a possible methodological artifact in stressor research. The authors hypothesized that certain aspects of the consent form may give the subject the perception of control over the stressor. Empirical support was found for this hypothesis. Analyses revealed that stressed subjects who were explicitly informed via consent forms of their freedom to withdraw from the experiment performed significantly better on cognitive tasks than stressed subjects not so informed.