BACKGROUNDDuring pregnancy there is immunological, metabolic, endocrine and vascular changes responsible for physiological and pathological skin changes.OBJECTIVESdetermine the prevalence of specific physiological changes and pregnancy, comparing the period of gestation of their appearances and compare type of prenatal care as the skin changes.METHODSA cross-sectional study with 905 pregnant women.RESULTSThe prevalence of physiological skin changes was 88.95% and the most common was pigment. The prevalence of specific dermatoses was 8.72% and atopic eruption was the most common.CONCLUSIONPhysiological changes were seen more in the 3rd quarter, as well as the specific dermatoses. No statistical difference in prenatal low risk compared to high risk was observed, whereas the cutaneous physiological changes and specific pregnancy dermatoses.
Resumo: A his tio ci to se de célu las de Langerhans é repre sen tan te de um raro grupo de sín dro mes his tio citá rias, sendo carac te ri za da pela pro li fe ra ção das célu las de Langerhans. Suas mani fes ta ções variam de lesão soli tá ria a envol vi men to mul tis sis tê mi co, sendo o aco me ti men to vul var inco mum. Segue-se o rela to de caso refra tá rio da doen ça limi ta da à pele, em mulher de 57 anos. A pacien te apre sen ta va his tó ria de pápu las erite ma to sas ulce ra das em couro cabe lu do, face, vulva, tron co e axila há seis anos. O diag nós ti co da doen ça é difí cil, sendo con fir ma do neste caso atra vés de estu do imuno-his to quí mi co e se obte ve res pos ta tera pêu tica e efi caz, com a admi nis tra ção de tali do mi da. Palavras-chave: Histiocitose; Histiocitose de célu las de Langerhans; Histiócitos Abstract:Langerhans cell his tiocy to sis is a mem ber of a group of rare his tiocy tic syndro mes and is cha racte ri zed for the pro li fe ra tion of his tiocy tes cal led Langerhans'cells. Its mani fes ta tions vary from a soli tary injury to syste mic invol ve ment, and vul var lesions are uncom mon. We des cri be a refrac tory case of cutaneous limi ted disea se in a 57-year-old woman. She pre sen ted with a 6-year his tory of an ery the ma tous papu lar erup tion of the scalp, face, vulva, trunk and axil lae. The diag no sis is dif fi cult and in this case it was con fir med through immu no his to che mi cal study and cli ni cal impro ve ment was achie ved with tha li do mi de.
Demonstra-se quadro raro de Elefantíase Nostra, na sua forma verrucosa, no dorso de pé de homem de 80 anos por episódios prévios de erisipela de repetição. As lesões confluentes vegetantes e difusas em dorso de pé são comparáveis aos corais Trumpet Coral (Caulastrea curvata)
BackgroundThe high-frequency ultrasound is a reliable method to identify enthesitis, including subclinical and early diagnosis, in patients with psoriasis (Pso) and psoriatic arthritis (PsA)1.ObjectivesTo establish an epidemiological profile of patients with Pso and/or subclinical and clinical PsA; to establish the ultrasound (US) profile with gray scale and Doppler in entheses in these groups.MethodsA case control study conducted in the period from December 2015 to December 2016, at Hospital das Clínicas/UFG. It was performed in 144 patients with Pso and/or PsA and 24 healthy controls. Patients with and without arthritis/enthesitis were submitted to the US. The US findings were according to the MASEI (the Madrid sonography enthesitis index). The entheses were studied bilaterally: plantar fascia, distal calcaneal tendon, distal and proximal ligament of the patella, distal quadriceps and tendons of the brachial triceps. In addition to the US in the 2nd and 3rd distal interfalanges. The interobserver reliability was calculated in 24 patients - kappa index (k).ResultsIn the case group the mean age was 50.13 years, BMI of 28.14; duration of illness of 16 years; Mean±SD PASI: 5.34±6,03; PEST:2,21±1,66 and DLQI:4.39±5,16. Of the total 90.3% of the patients presented Pso; 39.8% APs already diagnosed and 77.8% with signs of US enthesopathy. Of the total of the 1728 entheses evaluated in the case group and the control group of 288 structures evaluated. The most common sign in both groups was the thickening, being more seen in the calcaneus tendon (table). The MASEI score was significantly higher in patients with Pso and PsA than in the control group and had correlation with PEST: r= 0,397, p<0,001 and IMC: r=0,208, p= 0,012. Of the 288 nail insertion of the 2nd and 3rd distal interphalangeal, presented some type of enthesopathy to the US, like thickening (34,7%, p=0,036 to 0,003) or loss of the trilaminar pattern (31,6%, p= 0,027 to 0,004) and the most common change was positive PD (61,1%, p<0,001). Of the total nails evaluated only 17.5% had clinic injury. And the κ values weighted for the US findings showed excellent agreement (0.930 and 1) for PD and erosions, respectively. The epidemiological profile of patients with Pso and/or subclinical and clinical PsA were overweight. As for the US profile, the majority presented signs of enthesopathy, where the most frequent occurrence was the calcaneal tendon, and the Doppler was the most affected topography of the triceps tendon.ConclusionThe ultrasonography shows an important perspective in assessing entheses these patients.References[1] Kaeley, G. S., Eder, L., Aydin, S. Z., Gutierrez, M., & Bakewell, C. Enthesitis: A hallmark of psoriatic arthritis. Seminars in Arthritis and Rheumatism., 2018; 48(1), 35–43. Table: MASEI score: Ultrasound Findings Case (n=144) Control (n=24) p Number of entheses changed 1728 288 Structure ( n (%))472 (27,3)16 (5,6)< 0,001 Thickening ( n (%))503 (29,1)37 (12,8)< 0,001 Bursitis ( n (%))*95 (16,5)05 (1,73)0,004 Erosion n (%))48 (2,8)02 (0...
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