Objectives: The aim of this study was to investigate the conditions for viable lactic acid bacteria (LAB) cells and their heat-killed LAB, and the formulation as well as an alternative treatment to antibiotics to reduce infection, invasion and the inhibition of IL-8 secretion induced by S. choleraesuis for HT-29 cells.
Methods:To examined the efficacy of live LAB and heat-killed products in (1) inhibiting Salmonella choleraesuis growth by the plate agar-well diffusion assay, (2)
Conclusion:Both viable and heat-killed LAB powder products were potentially useful for the protection of the epithelial cells against Salmonella infection, invasion and the induced inflammation for swine and human.
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