Although knowledge on medicine acceptability remains fragmented, this multi-faceted concept has emerged as a key factor for compliance in pediatrics. In order to investigate the acceptability of medicines used in the University Medical Centre Ibn Sina (CHIS) of Rabat, Morocco, an observational study was conducted. Using a multivariate approach integrating the many aspects of acceptability, standardized observer reports were collected for 570 medicine intakes in patients up to the age of 16, then analyzed on a reference framework. Tablets appeared to be well accepted in children greater than 6 years old, but were crushed/dissolved for 90% of the 40 children aged from 3 to 5, and 100% of the 38 patients younger than 3. Moreover, the prescribed dose was fully taken for only 52% and 16% of these younger children, respectively. Despite this, tablets represented 24% of evaluations in children from 3 to 5 and 20% in infants and toddlers. Oral liquid preparations appeared to be better accepted than tablets in preschoolers, but not for those under 3. Overall, these findings highlight the lack of suitable alternatives for the younger children, especially for formulations of antiepileptics, antithrombotic, and psycholeptic agents in the local context.

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Les complications oculaires post radiques sont fréquentes au cours de l'irradiation des tumeurs de la tête et du cou. Certaines sont bénignes et transitoires, d'autres peuvent être très graves pouvant mettre en jeu la fonction visuelle. Nous discuterons à travers ce cas rare et inhabituel, les différentes manifestations et complications oculaires et surtout cornéenne de la radiothérapie ainsi que les modalités diagnostiques et thérapeutiques d'une perforation cornéenne qui représente une complication redoutable de la radiothérapie.

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