The aim of this cross-sectional study was to assess the health status and quality of life (QOL) of paid unrelated versus related living kidney donors postdonation at Shiraz Transplant Center in Iran. We invited all donors (n ¼ 580, 347 paid unrelated, 233 related) who underwent donor nephrectomy at our center from 2004 to 2010 to participate in a health survey and physical examination. Of 580 donors, 144 consented to participate; participation of paid unrelated donors was significantly lower than related (52/347 vs. 92/233; p < 0.001). Participants underwent a complete physical examination, QOL assessment (using a 36-item short form health survey [SF-36] questionnaire) and laboratory work-up. The paid unrelated donors compared with related donors were younger (34.2 AE 7.2 vs. 40.7 AE 9.7 years, p < 0.001), had shorter time since donation (2.9 AE 1.6 vs. 3.8 AE 2 years, p ¼ 0.004), had higher estimated GFR (72.6 AE 22 vs. 63.8 AE 15.3 mL/min/ 1.73 m 2 , p¼ 0.006) and had a higher percentage of patients with microalbuminuria (35% vs. 0%, p < 0.001). Additionally, general health and social functioning scores among paid unrelated donors were significantly lower (p < 0.001 and p ¼ 0.02, respectively) than related donors. Other SF-36 scores, although lower in paid unrelated donors, did not reach statistical significance. Iranian paid unrelated donors have lower QOL and higher incidence of microalbuminuria compared with related donors.
Enabling informed policymaking for chronic kidney disease with a registry: initiatory steps in Iran and the path forward, Health Policy and Technology, https://doi.org/10. 1016/j.hlpt.2018.01.004 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Chronic kidney disease (CKD) registries have been used for more than half a century. Iran lacks a comprehensive registry to capture data of all CKD patients for an informed care planning and policy making. We aimed to identify the objectives and possible challenges for developing a CKD registry and also to define its minimum data set (MDS)in our healthcare context. MethodsThis was a mixed-method study conducted in Iran from fall 2016 till summer 2017. The qualitative part included document analysis and 26 semi-structured interviews with 17 clinicians and managers involved in CKD care. This data was analyzed using the "grounded theory". Then, a modified Delphi survey was conducted. Percentages and mode values were used for analysis. ResultsOur participants' leading interest in a CKD registry was centered on providing a coordinated, qualitative care for all CKD stages with particular emphasis to capture events and monitor trends for patients in earlier stages. They highlighted the required financial, technical and human resources as main challenges for a smooth registry implementation. Furthermore, a clinically oriented MDS comprising of 168 elements (with a majority having more than 90% agreement with mode 2) was extracted. It mainly collects demographics, medical history, encounter sessions, diagnostic examinations, medications, vaccinations and mortality data. Conclusions 3We reported the initiatory steps taken to establish a CKD registry in an Iranian healthcare context. We focused on the information needs and priorities of our main stakeholders and based our intended registry on addressing those needs. We hope this approach will facilitate its endorsement and advance the efforts for a sustainable, qualitative CKD care.
BACKGROUND:The nasal septum deviation is the most common deformity of the nasal, and that can be congenital or acquired. Despite many studies exist about the impact of nasal septum deviation on chronic sinusitis and also association between chronic otitis and mastoid pneumatization; few studies exist about the impact of nasal septum deviation on chronic otitis and mastoid pneumatization.AIM:The aim of this study was to evaluate the associations of nasal septum deviation and mastoid pneumatization and chronic otitis.METHODS:In this study review, all CT scans of PNS and Mastoid View in the imaging section from Imam Ali hospital in 2016-2017 years and cases of nasal septum deviation were enrolled. The nasal septum deviation was recorded, and the degree of nasal septum deviation in the coronal plane that showed the maximum deviation of the nasal septum was recorded. The volume of the mastoid cells automatically and directly was calculated using three diameter measurements (2 coronal diameters and 1 axial diameter) by the program. The software of SPSS 22 was used for statistical analysis.RESULTS:There was no relationship between nasal septum deviation severity and incidence of mastoid pneumatization in patients with nasal septum deviation (P > 0.05). There was relationship between nasal septum deviation severity and chronic otitis in patients with nasal septum deviation (P < 0.05). In patients with moderate and severe intensity of nasal septum deviation, the volume of mastoid air cells in deviation side was lower than the front side (P < 0.05).CONCLUSION:Based on the results of the CT scan, in patients with moderate and severe nasal septum deviation intensity, the volume of mastoid air cells in deviation side was lower than the front side. Also, there was a relationship between nasal septum deviation severity and chronic otitis.
INTRODUCTION AND AIMS:Gingival overgrowth (GO) is the main oral manifestation in transplant recipients (TR). The risk factors for GO occurrence are calcineurin inhibitors, bacterial dental plaque, gingival inflammation index, calcium channel blockers, transforming growth factor-beta, HLA-A24, IL-1A polymorphisms and downregulation of matrix metalloproteinase levels in gingival fibroblast. Interestingly some risk factors for atherosclerosis such as bacterial dental plaque and gingival inflammation are similar with risk factors of GO. So we suggest that there may be a correlation between GO and atherosclerosis. METHODS: In this cross sectional case control study we enrolled 343 renal TRs which received their allograft between 1997-2004. Carotid intimal medial thickness (CIMT) as a marker of atherosclerosis was measured by ultrasonography in TRs by one radiologist and the CIMT 7.5 mm considered positive. All TRs were examined by one dentist and GO scoring determined based on Mc Gaw scoring system. Other demographic and clinical data obtained from medical records and the RTs and entered in the questionnaire. data was analyzed using chi-square, T test and logistic regression. RESULTS: Among 343 RTs 57.7% were male, mean age was 40.54 13.08 years. CIMT 7.5 mm was found in 33.8% of RTs. GO was found in 37.6% of RTs. Mean of follow up from transplantation was 74.88
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