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Silver nanoparticles (Ag NPs) were synthesized using Alternanthera sessilis leaf and Oregano root extract in an eco-friendly fashion and their significant physicochemical and optochemical properties were ascertained for nano-defined characteristics. The UV-visible spectrum showed a single and distinct absorbance peak at 433 nm (Alternanthera sessilis) and 425 nm (Oregano), typical SPR (surface plasmon resonance) for silver. Structural studies revealed nano-crystal with face centre cubic (FCC) symmetry with monodispersed nature. SEM studies showed spherical-shaped particles and the purity determined from EDX spectrum. The synthesized Ag NPs showed that antibacterial activity was studied. There was a significant inhibitory effect toward clinically important pathogens viz. B. subtilis, S. aureus, P. aeruginosa, and E. coli exposed to Ag NPs at different concentrations.

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One of the emerging technologies of the recent times harboring nanotechnology to fabricate nanofibers for various biomedical and environmental applications are electrospinning (nanofiber technology). Their relative ease in use, simplicity, functionality and diversity has surpassed the pitfalls encountered with the conventional method of generating fibers. This review aims to provide an overview of electrospinning, principle, methods, feed materials, and applications toward tissue engineering. To begin with, evolution of electrospinning and its typical apparatus have been briefed. Simultaneously, discussion on the production of nanofibers with diversified feed materials such as polymers, small molecules, colloids, and nanoparticles and its transformation into a powerful technology has been dealt with. Further, highlights on the application of nanofibers in tissue engineering and the commercialized products developed using nanofiber technology have been summed up. With this rapidly emerging technology, there would be a great demand pertaining to scalability and environmental challenge toward tissue engineering applications.

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In this work, nanospherical hydroxyapatite (HAP) was prepared that has combined properties of controlled drug delivery, biocompatibility, and antibacterial activity to have applications in the biomedical sector.