Hepatitis C viruses (HCV) present in 110 Italian patients were characterized by genotype-specific PCRs. Among the 65 cases of community-acquired hepatitis, HCV genotype IT was dominant (60%o), followed by genotypes IV (15%), m (11%), and I (3%). Among the 45 hemophilia-associated cases, the distribution of the

We studied the incidence of specific antibodies to interferon-a2 (IFN-a2) in 251 patients with chronic hepatitis C treated with recombinant IFN-a2a, and the time when these antibodies developed. Neutralizing antibodies (N.Ab) were found in 23.1% of the patients, and binding antibodies (B.Ab) in Address reprint requests to:

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