Methods for the synthesis of secondary aromatic amines containing 1,3-benzodithiol or 4-aryl-1,3-dithiol cycles have been developed. The antimicrobial activity of the synthesized compounds has been determined.As is known, 1,3-dithiol derivatives exhibit biological activity of various types, including bactericidal, fungicidal [1], and diuretic [2]. In order to obtain new compounds of this class with potential biological activity, we have studied reactions between 1,3-benzodithiolium salts with secondary aromatic amines.According to the published data, N-methylaniline interacts with 1,3-benzodithiolium tetrafluoroborate to form a tertiary amine [3]. We established that reactions of 1,3-benzodithiolium perchlorate (I) and 4-aryl-1,3-dithiolium perchlorates (IIa -IIc) with N-arylmethylanilines (IIIa -IIIe) yield N-[4-(1,3-Benzodithiol-2-yl)phenyl]-N-arylmethylamines (IVa -IVc) and N-[4-(4-aryl-1,3-dithiol-2-yl)phenyl]-Narylmethylamines (Va -Vg).The synthesized compounds appear as crystalline substances with a light pinky tint, which deepens with time. The products are soluble in hexane, ethanol, and benzene and insoluble in water. The yields and physicochemical characteristics of the synthesized compounds IV and V are presented in Table 1. The proposed structures were confirmed by the results of 1 H NMR spectroscopy measurements ( Table 2).The 1 H NMR spectra of compounds IV and V contain, in addition to the signals from aromatic protons, a broad singlet due to protons of the NH group (d = 3.90 -4.15 ppm) and a singlet due to protons at the second carbon atom of the dithiol cycle (6.01 -6.17 ppm). The signal from protons of the methylene group at NH is not split [4] and appears as a singlet at 4.17 -4.26 ppm. In the spectra of compounds Va -Vg, the protons of methine groups at position 5 of the heterocycle give a singlet at 6.25 -6.27 ppm. II: R 3 = H (a), Br (b), Cl (c); III: R 1 = R 2 = H (a), R 1 = OCH 3 , R 2 = H (b), R 1 = R 2 = OCH 3 (c), R 1 = Cl, R 2 = H (d), R 1 = Br, R 2 = H (e);