✓ A new isotopic method for the detection of cerebral tumors using labeled bleomycin is described. In a series of 104 patients, bleomycin was found superior to technetium-99m for the diagnosis of intracranial metastatic lesions; in 50% of the cases, bleomycin revealed metastases undetected by the Tc-99m, particularly in the posterior fossa. This method also provides valuable data for the differentiation of gliomas from metastases.
The authors describe their technique for identifying and localizing posttraumatic cerebrospinal fluid fistulas. The method entails injection of radionuclide tracer into the subarachnoid frontal space with the patient in a sitting position followed by gamma camera scintigraphic recordings. The results in 308 patients are presented; these are compared with those of suboccipital radionuclide cisternography in 40 cases and metrizamide computerized tomography cisternography in nine cases. Transient complications occurred in only three patients.
✓ A new use of radioisotopic cisternography in diagnosing cerebellopontine tumors is reported, and the value both in positive and topographic diagnoses stressed. Isotopic investigation seems to be a useful adjunct to the conventional method of detection.
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