The interaction between two metals, which can be either synergistic or antagonistic, implies that the behavior of one is changed by the presence of the other. Possible mechanisms of these interactions, whkh include chemical association, competition for carriers, metabolic changes, induction of binding proteins, membrane alterations are discussed.The interactions between toxic compounds is a loose term which implies that the behavior or effect of one compound is changed by the administration or presence of another. It does not imply that the two compounds interact chemically, although chemical reaction between them or their metabolites is possible. Studies on the interaction between metals are only in an early phase and do not permit the development of generalizations or classifications.
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