prior conventional cancer treatments including surgery, chemotherapy, radiotherapy, hormone and immunotherapy and dissatisfaction, defined by concerns that conventional treatment was ineffective, too expensive, or associated with intolerable side effects. Results: Of the 778 campaigns analyzed, 68.3% (531) campaigns contained themes of dissatisfaction. Of those 531, 41.8% (222) reported having had surgery, 49.5% (263) reported having had chemotherapy, 28.6% (152) radiotherapy, 3.0% (16) hormone therapy, and 2.6% (14) immunotherapy. Significant independent predictors of dissatisfaction were prior use of chemotherapy (Odds Ratio [OR]: 1.93, 95% Confidence Interval [CI]:1.34-2.83) and having Stage IV cancer (OR: 2.29, 95% CI:1.65-3.20). No other therapies or cancer types were significantly associated with dissatisfaction. Conclusion: Prior use of radiation therapy, surgery, hormone therapy, and immunotherapy were not independent predictors of dissatisfaction, nor were the individuals' cancer types; however, chemotherapy was an independent predictor of dissatisfaction when controlling for other important factors as reported in crowdsourcing campaigns seeking financial assistance for alternative cancer therapies. This information highlights the importance of doctor-patient communication regarding complications of and expectations for cancer treatment.
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