The purpose of this study is to highlight the role of multidetector CT (MDCT) in emergency radiology as a useful tool in the diagnosis and management of acute female pelvic disease and to describe key radiologic signs to improve differential diagnosis. We restrospectively reviewed MDCT findings of acute pelvic disease and its mimics in women reporting to the emergency room at our institution from December 2006 to August 2008. We describe MDCT findings of gynecologic and obstetric disorders such as hemorrhagic ovarian cysts, ovarian torsion, pelvic inflammatory disease, ruptured ectopic pregnancy, intravascular leiomyomatosis, blunt maternal trauma, and postpartum and post-cesarean section complications. We also briefly review gastrointestinal tract entities that may mimic these conditions. Although ultrasound is the imaging modality of choice for the evaluation of female pelvic pain, the role of MDCT remains essential in the management of patients in which gynecologic exploration is not diagnostic or undone since it is not the initial suspicion.
Objective
To determine the predictive factors of pulmonary thromboembolic (PTE) in patients with SARS-CoV-2 infection (COVID-19) assessed in the emergency department at a tertiary hospital during the first pandemic wave.
Methods
Observational single-center study conducted in a retrospective cohort of patients with confirmed SARS-CoV-2 infection (or high clinical-radiological suspicion) who underwent PTE screening by computed tomography pulmonary angiography (CTPA). Predictive factors of PTE were explored using logistic regression, creating two predictive models (without or with D-dimer values).
Results
Out of a total of 274 CTPA performed, 70 procedures presented diagnostic findings of PTE, representing a cumulative incidence of 25.54% (95% confidence interval [CI]: 20.49–31.14). In the non-D-dimer based model, respiratory rate >22 bpm (odds ratio [OR]: 3.162; 95% CI: 1.627–6.148; p = 0.001) and the absence of findings suggestive of COVID-19 in plain chest X-ray (OR: 3.869; 95% CI: 0.869–17.225; p = 0.076) were predictors of PTE. In the D-dimer-based model, tachypnea remained as a predictive factor (OR: 4.967; 95% CI: 2.053–12.018; p < 0.001), as well as D-dimers > 3,000 ng/ml (OR: 7.494; 95% CI: 3.038–18.485; p < 0.001).
Conclusions
The presence of tachypnea (>22 bpm) and the absence of radiological findings suggestive of SARS-CoV-2 infection in the chest X-ray, in addition to D-dimer values >3000 ng/mL, were identified as predictive factors of PTE in patients with COVID-19.
Introducción
El coronavirus SARS-CoV-2, responsable de la pandemia actual, afecta preferentemente al tracto respiratorio, con un número creciente de publicaciones sobre su predisposición a fenómenos trombóticos.
Objetivo
Conocer la prevalencia de tromboembolismo pulmonar (TEP) en pacientes con COVID-19; determinar su posible relación con la gravedad de la enfermedad pulmonar y los niveles de dímeros-D, y analizar la localización del TEP en pacientes con COVID-19 comparándolos con los negativos.
Método
Estudio retrospectivo de todas las angio-TC de arterias pulmonares por sospecha de TEP del 15 de marzo al 30 de abril de 2020. Se compara con las angio-TC realizadas durante el mismo periodo en 2019.
Resultados
Se incluyeron 492 angio-TC pulmonares, 342 (69,9%) de pacientes con COVID-19 y 147 (30,1%) de pacientes sin infección. La prevalencia de TEP fue del 26% en el grupo COVID-19 positivo y del 16,3% en el negativo (
p
=0,0197), con un riesgo relativo de 1,6 veces. La prevalencia de TEP en el mismo período del año 2019 fue del 13,2%, similar a la del grupo COVID-19 negativo del año 2020 (
p
=0,43). No hubo diferencias significativas en el nivel de dímeros D ni en la localización del TEP entre ambos grupos. El 78,7% de los pacientes con COVID-19 con TEP mostraron una extensión de la afectación pulmonar moderada o grave en la tomografía computarizada.
Conclusiones
Los pacientes con COVID-19 tienen una prevalencia aumentada de TEP (26%) y la mayoría (78,7%) presentan una extensión moderada o grave de afectación pulmonar en la tomografía computarizada. No hay diferencias significativas en la localización del material embólico ni en el grado de elevación de dímeros D respecto a los pacientes sin COVID-19.
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