The results of analysis of cardiovascular and psychosocial risk factors which influence the development and prediction of ischemic heart disease (IHD) and disorders of carbohydrate and lipid metabolism in 132 patients with neurotic and affective disorders are presented.
Two clinical cases that demonstrate the difficulties diagnosing the causes of shortness of breath, coupled with anxiety, are analyzed. From the standpoint of modern neurophysiology it explains the relationship of these conditions. There were revealed typical diagnostic mistakes: «the effect of precocious focusing", "the negative effect of the narrow specialization
Objective. To assess the effectiveness original Indapamide (Arifon Retard, Servier, France) in patients with arterial hypertension and type 2 diabetes mellitus. Design and methods. 30 hypertensive subjects (mean age — 55 ± 4,0 years) with type 2 diabetes mellitus and uncontrolled hypertension, who took any of generic forms of Indapamide. Generic forms were substituted by original drug in all subjects (Arifon Retard). The follow-up lasted for 3 months. We assessed blood pressure changes, achievement of target blood pressure level, the changes of blood pressure according to 24-hout blood pressure monitoring. All subjects also filled in the questionnaires on life quality MOS SF-36 (MOS 36-ltem Short-Form Health Survey). Results. The mean decrease of blood pressure was 29/15 mm Hg. 80 % patients achieved target blood pressure levels. The therapy with original form of Indapamide was safe. We observed the decrease of plasma glucose level, of serum levels of total cholesterol, triglycerides, and low density lipoproteins, while there was a slight increase of the level of high density lipoproteins. According to the survey, the quality of life (MOS SF-36) the indicators of physical and mental health considerably increased. Results. Original Indapamide shows benefits in controlling blood pressure in high risk subjects, in particular, in hypertensive patients with type 2 diabetes mellitus.
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