Medical Image Processing is the technique of analysing medical image such as CT, MRI for diagnostic and treatment purpose. The role of image compression is vital in domain of tele medicine for storage and transmission of medical data. In this project transform domain based compression algorithm is employed for the efficient compression and transfer of medical data. The Discrete Cosine Transform (DCT) based fractal image compression algorithm is employed for real time CT medical image. The result is validated by performance metrics Peak Signal to Noise Ratio (PSNR) and compression ratio. The algorithm was developed in MATLAB 2010a.
The effect of bilirubin on cellular energy metabolism has been studied in vitro. Bilirubin inhibits oxidative phosphorylation in isolated rat-liver and brain mitochondria, with a depression of the underlying respiration as a concomitant phenomenon. The latter effect can be prevented by the addition to the mitochondrial suspensions of diphosphopyridine nucleotide and cytochrome C.
In experiments with rabbits in vivo it has been shown that the penetration of bilirubin from blood into central nervous system is greatly enhanced by intracisternal treatment with p-chloromercuribenzoate, an agent which inhibits the function of the blood-brain barrier system. The increase of the concentration of bilirubin in the cerebrospinal fluid upon treatment with p-chloromercuribenzoate is parallelled by an equal increase of the total protein content.
The bearing of these findings on the pathogenesis of kernicterus, and some of the clinical implications are discussed.
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