The TNM system is used to describe and classify cancer stages and progression based on the assessment of three components: T The extent of the primary tumour N The absence or presence and extent of regional lymph node metastasis M The absence or presence of distant metastasis. TNM classification for the above site is described under the following headings: Rules for classification with the procedures for assessing T, N, and M categories; additional methods may be used when they enhance the accuracy of appraisal before treatment Anatomical sites and subsites where appropriate Definition of the regional lymph nodes TNM Clinical classification pTNM Pathological classification G Histopathological grading Stage grouping Summary

The TNM system is used to describe and classify cancer stages and progression based on the assessment of three components: T The extent of the primary tumour N The absence or presence and extent of regional lymph node metastasis M The absence or presence of distant metastasis. TNM classification for the above site is described under the following headings: Rules for classification with the procedures for assessing T, N, and M categories; additional methods may be used when they enhance the accuracy of appraisal before treatment Anatomical sites and subsites where appropriate Definition of the regional lymph nodes TNM Clinical classification pTNM Pathological classification G Histopathological grading Stage grouping Summary

The TNM system is used to describe and classify cancer stages and progression based on the assessment of three components: T The extent of the primary tumour N The absence or presence and extent of regional lymph node metastasis M The absence or presence of distant metastasis. TNM classification for the above site is described under the following headings: Rules for classification with the procedures for assessing T, N, and M categories; additional methods may be used when they enhance the accuracy of appraisal before treatment Anatomical sites and subsites where appropriate Definition of the regional lymph nodes TNM Clinical classification pTNM Pathological classification G Histopathological grading Stage grouping Summary

The site is described under the following headings: Rules for classification with the procedures for assessing T, N, and M categories; additional methods may be used when they enhance the accuracy of appraisal before treatment Anatomical subsites Definition of the regional lymph nodes TNM Clinical classification pTNM Pathological classification G Histopathological grading R Classification Stage grouping Summary

The following sites are included: Vulva Vagina Cervix uteri Corpus uteri Ovary Fallopian tube Gestational trophoblastic tumours Cervix uteri and corpus uteri were among the first sites to be classified by the TNM system. The “League of Nations” stages for carcinoma of the cervix have been used with minor modifications for over 50 years, and, because these are accepted by the Fédération Internationale de Gynécologie et d'Obstétrique (FIGO), the TNM categories have been defined to correspond to the FIGO stages. Some amendments have been made in collaboration with FIGO, and the classifications now published have the approval of the FIGO, UICC, and the national TNM committees including the AJCC. Each site is described under the following headings: Rules for classification with the procedures for assessing T, N, and M categories; additional methods may be used when they enhance the accuracy of appraisal before treatment Anatomical subsites where appropriate Definition of the regional lymph nodes TNM Clinical classification pTNM Pathological classification Stage grouping Summary