Local administration of rhGH during the surgical placement of titanium sheets on the tibiae of an osteoporotic rabbit model enhances periosteal and transcortical reaction and mineralization of osteoid 14 days later around titanium sheets, without increasing bone resorption.

We report a study of 28 women with severe primary gonarthrosis followed for 1 year. Variations in bone mineral density and in functional behaviour of knee extensors and flexors were studied before and after implantation of uncemented total knee prosthesis. A functional deficit was noted in the extensor apparatus, which increased in the first 6 months following surgery. This strength was not improved 1 year following the arthroplasty, but it was more efficient as shown by the reduction of muscle fatigue. Flexor strength was conserved and a pathological muscle balance was maintained, reaching maximum efficiency over a smaller joint range.Résumé Etude des variations de la densité minérale osseuse et du comportement des extenseurs et fléchisseurs du genou avant et après implantation d'une prothèse totale non cimentée chez 28 femmes souffrant d'une gonarthrose primaire sévère et suivies pendant une année. Un déficit fonctionnel de l'appareil de l'extenseur à été noté avant l'intervention et a augmenté dans les six premiers mois suivant la chirurgie. La force d'extension n'était pas améliorée une année après l'arthroplastie, mais l'action était meilleure à cause d'une moindre fatiguabilité du muscle. La force des fléchisseurs a été conservée et un équilibre musculaire a été maintenu, en arrivant à l'efficacité maximale sur une plus petite amplitude articulaire.

This paper shows the distribution of the body compartments, and the age and gender related changes in Spanish children. Subjects and Methods: A total of 231 healthy children from Madrid (Spain) were recruited and divided into 3 groups according to age (birth-5, 6-10, 11-15y). Body compartments (fat mass, lean mass and bone mass) measures were obtained from dual energy X-ray absorptiometry (DXA) scans. Total and regional body compositions were evaluated. Results: There were gender differences for TBFM (total body fat mass) in 11 - 15 year age group and for TLBM (total lean body mass) in all age groups except for the 6 - 10 year age group. TBMC (total bone mineral content) shows significant gender differences form birth. Conclusions: Contrary to boys, girls showed from early infancy a smaller proportion of muscle mass and a higher proportion of body fat (from the age of 10), with fat deposits being mostly peripheral. Bone mass and muscle mass values were higher in boys