A 34-year-old man with a recent HIV diagnosis presented to the emergency department with a holocranial headache and skin lesions due to cryptococcosis. He was admitted and during treatment, he presented nausea, persistent vomiting, and epigastric pain. Esophagogastroduodenoscopy revealed multiple round lesions with reddish elevated edges and a pale center in corpus and antrum which were positive for Cryptococcus in pathology analysis.
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