Background: Previous studies have shown contradictory findings regarding the effects of systolic blood pressure variability (SBPV) after intravenous thrombolysis (IVT) on functional outcomes and risk of intracranial hemorrhage (ICH) in acute ischemic stroke (AIS).Objective: The purpose of this systematic review and meta-analysis was to ascertain how SBPV indices, successive variance of SBPV (SPBVsv), following IVT affected the outcome in AIS.Method: We searched for articles published before October 2022 in the following databases: PubMed, Scopus, ScienceDirect, and ProQuest. The pooled multivariate odds ratios (ORs) and 95% confidence intervals (CIs) were obtained using Jeffrey's Amazing Statistics Program (JASP). The outcomes included favorable functional result using modified Rankin Scale (mRS) score less than 2 within 90 days and intracranial hemorrhage event within 36 hours after IVT. The Newcastle Ottawa Scale (NOS) was used to rate the reliability of the studies.Result: Initial search revealed 2089 studies, of which 8 studies including 31791 patients with AIS and underwent IVT met the inclusion criteria. Increased of SBPVsv following IVT was substantially related with a poorer functional result in AIS (OR = 2.72, 95% CI 1.38 to 5.36, I2 = 93.8%, p value of Q test 0.004) and increase risk of ICH (OR = 1.46, 95% CI 1.01 to 2.12, I2 = 73.6%, p value of Q test 0.043)Conclusion: Successive systolic blood pressure variability has a negative relationship with 90-days outcome in AIS patients who received IVT while the risk of ICH within 36 hours after IVT is increase.
total of 90 residents were enrolled from Posbindu in the Seroja Health Care Working Area stratified with purposive sampling for a month. A face-to-face questionnaire survey was conducted by trained investigators.Result: This study shows that the patient percentages with good knowledge are 67.8%, 12,2% with sufficient knowledge, and 20% with poor knowledge of hypertension. 62.2% of respondents were not obedient to having hypertension medication. The Chi-Square test shows the value of probability p value 0.001 (p 0.001, r = 0.374). Conclusion: There is a significant relationship between the level of knowledge and medication compliance in hypertensive patients at Posbindu in the Seroja Health Care Working Area.
Background: It is associated with target-organ damage in various organs and ECG changes. P-wave durations and P-wave dispersion (PWD) are considered to reflect the heterogeneous conduction in atria.Objective: The aim of this study was to investigate relationship PWD and P-wave duration and left ventricular hypertrophy in hypertensive heart disease patients.Method: This study was a-single centre, retrospective study, included 55 consecutive patients with hypertension who had visited the cardiology clinic. Elektrocardiography (ECG) and transthoracal echocardiography (TTE) were performed. Patient were divided into LVH group and control group baed on TTE findings. Patients with valvular regurgitation (moderate or severe), valvular stenosis, myocardial infarction, LV dysfunction, pericardial disease, chronic obstructive pulmonary disease (COPD), bundle branch blocks, atrial fibrillation or flutter were excluded from the study.Results: We found 31 hypertensive patients (56%) had LVH by TTE. The mean age for the HHD was 57 ± 11 years while the control group was 56 ± 11. In the HHD group, maximum P-wave duration was significantly increased at 119.31 ± 13.60 ms, compared to 97.14 ± 18.20 ms in the control group (p < 0.001). There was also a significant increase in minimum P-wave duration in HHD group at 59.65 ± 15.56 ms, compared to control group with 53.33 ± 14.60 ms (p = 0.004). There was a significant increase in the PWD in the hypertensive group at 59.31 ± 19.62 ms, compared to controls with 43.80 ± 17.54 ms (p < 0.001).Conclusion: PWD was significantly increased in hypertensive patient with left ventricular hypertrophy.
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