The prostate epithelium of rats which received repeated cadmium chloride (CdCl2) injections showed a gradual disruption of structural differentiation. Electron microscopy studies revealed severe changes in the ultrastructure affecting all epithelial cell organelles, particularly the nuclei, rough endoplasmatic reticulum, the golgi apparatus, and mitochondria. The cells infiltrating the stroma contained secretory vacuoles and their nuclear evaginations on the invasion front showed similarities to ultrastructural pathological changes in man. Examinations of the ventral prostate following oral CdCl2 administration revealed changes ranging in severity up to dysplasia, but there was no evidence of carcinoma.
Black needles were compared to silver needles for quantity of reflected light and ease of laparoscopic visualization. The black needles reflected less light and were thus more easily visualized during laparoscopic surgical procedures. The silver needles resembled a mirror in that they reflected incident light from both the light source and light from the surrounding tissue.
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