Brief Communications 635The tumor was sectioned into serial 1 mm thick undecalcified slabs on a low speed saw using a diamond coated circular blade (Fig. 2). Radiographs were then made of the undecalcified sections using high contrast photographic film. Following radiography, the sections were decalcified with citrate buffered formic acid, embedded, and sectioned at 6 pm. High resolution radiographies clearly demonstrated that all the hard matrices of normal tooth formation, dentin, enamel, and cementum, were fully differentiated and also mineralized within this tumor (Fig. 3). Decalcified sections from less completely mineralized areas showed a wider variety of dental differentiation, ranging from purely epithelial structures reminiscent of early enamel organ formation to deposits of dentin, enamel, and cementum (Figs. 4, 5). The fact that all features of normal tooth formation were present, differentiated, and mineralized yet completely disorganized, suggests the diagnosis of complex odontoma.An interesting feature of this complex odontoma is the formation of cementum matrix. Cementum matrix has not been reported as a feature of complex odontomas in simple toothed animals. Possibly the presence of cementum in this case might be explained by the difference in tooth formation in animals with continuously erupting compound teeth, compared with animals that have simple teeth, such as humans and carnivores. In compound teeth, as soon as the ameloblastic epithelium disappears, the exposed enamel surface becomes covered with cementum, whereas in simple teeth, cementum and enamel never juxtapose. Cementum formation on enamel matrix was seen in both heavily mineralized and less mineralized areas of the tumor. This tendency for cementum formation induction to occur in association with exposed enamel is typical of compound tooth odontogenesis.5 This probably explains this interesting difference in the complex odontoma of this compound toothed animal compared to that seen in people and carnivores. Horsepox or contagious pustular dermatitis is a benign, highly contagious disease of horses caused by an epitheliotropic, unclassified DNA p o x v i r~s .~~~~~~~ Horsepox in horses takes two forms, the "buccal-type" and/or the "greasy-heelt y~e . "~,~,~ The buccal form is characterized by the appearance of multiple eruptions and pocks on the inner surface of the lips and cheeks, gums, tongue, anterior nares, and face.2.5 The "greasy-heel-type" is manifested by the appearance of papular eruptions on the flexor surface of the joints in the lower part of the leg.2-5 These gross findings plus the presence of large, eosinophilic, intracytoplasmic pox inclusions in vacuolated keratinocytes are considered pathognomonic for this disease. Horsepox has not been reported in the United Molluscum contagiosum, another cutaneous poxvirus infection, was reported in a yearling colt.8 ReferencesA 10-year-old, 160 kg, female Sicilian donkey from the Sunset Zoo at Manhattan, Kansas was euthanatized because of proliferative, eruptive lesions of the ...
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