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After the 2011 accident at the Fukushima Daiichi nuclear power plant, nursing-home residents and staff were evacuated voluntarily from damaged areas to avoid radiation exposure. Unfortunately, the evacuation resulted in increased mortalities among nursing home residents. We assessed the risk trade-off between evacuation and radiation for 191 residents and 184 staff at three nursing homes by using the same detriment indicator, namely loss of life expectancy (LLE), under four scenarios, i.e. “rapid evacuation (in accordance with the actual situation; i.e. evacuation on 22 March),” “deliberate evacuation (i.e. evacuation on 20 June),” “20-mSv exposure,” and “100-mSv exposure.” The LLE from evacuation-related mortality among nursing home residents was assessed with survival probability data from nursing homes in the city of Minamisoma and the city of Soma. The LLE from radiation mortality was calculated from the estimated age-specific mortality rates from leukemia and all solid cancers based on the additional effective doses and the survival probabilities. The total LLE of residents due to evacuation-related risks in rapid evacuation was 11,000 persons-d—much higher than the total LLEs of residents and staff due to radiation in the other scenarios (27, 1100, and 5800 persons-d for deliberate evacuation, 20 mSv-exposure, and 100 mSv-exposure, respectively). The latitude for reducing evacuation risks among nursing home residents is surprisingly large. Evacuation regulation and planning should therefore be well balanced with the trade-offs against radiation risks. This is the first quantitative assessment of the risk trade-off between radiation exposure and evacuation after a nuclear power plant accident.

To assess the effects of policy measures taken to ensure health and promote well-being, we developed a novel indicator, "loss of happy life expectancy" (LHpLE), under the concept that an objective of life is maximization of lifelong happiness, by using objective survival probabilities and a simple question regarding emotional happiness: "Did you experience a feeling of happiness yesterday [yes/no]?" We measured the emotional happiness of 4990 Japanese respondents through a questionnaire. We then used LHpLE to compare risks after the 2011 Fukushima disaster. LHpLE due to psychological distress was estimated from a decline of emotional happiness, whereas that due to radiation exposure was assessed from shortened life expectancy caused by additional cancer mortality. LHpLE values due to psychological distress in evacuees were approximately 1 to >2 orders of magnitude higher than those due to cancer mortality caused by actual radiation exposure, highlighting the importance of measures to minimize distress following public health emergencies. LHpLE could be used for integrated risk comparison among different types of harms and therefore in government policy-making.

Precursors from rabbit CE were isolated by a sphere-forming assay. Rabbit CE-derived sphere therapy is an effective treatment in a rabbit CE deficiency model.

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Following the Fukushima incident, radiation doses from external exposure accounted for the majority of the total doses. Although countermeasures are being implemented, with the aim of reducing radiation exposure, little information is available on the effects of decontamination on individual doses among the residents of radioactively contaminated areas. To evaluate the effectiveness of the decontamination measures in reducing individual doses, and to examine the influence of the timing of decontamination and the district, data were analysed for 18 392 adults and 3 650 children in Minamisoma City, Fukushima, who participated in a voluntary screening programme using individual radiation dosimeters (Glass Badge) between June 2013 and September 2016. The dose reduction rates (DRR) were calculated for one year by comparing the first and last three-month measurement results between areas with and without decontamination. Using a regression approach and Monte Carlo simulation, the dose reduction rate by decontamination eliminating the effect of physical decay (DRRd′) was also estimated as a function of the timing of the decontamination and the dose at the time of starting the decontamination. The annual DRR in areas with decontamination for both adults and children were significantly higher than those in areas without decontamination, depending on the timing of decontamination: 31%–36% for 2013–14 for adults in decontamination areas and 33%–35% for children in decontamination areas, compared to 12%–23% and 13%–23% for adults and children in areas without decontamination, respectively. There was a positive correlation between DRRd′ and individual doses, and DRRd′ was estimated at 30%–40% for adults and children with doses of 3 mSv y−1 in 2013 and 2014. This study demonstrated that decontamination does lower individual doses from external exposure. The higher the dose at the time of starting the decontamination, the greater the dose reduction rate by decontamination, regardless of the timing of the decontamination. Our study confirms that decontamination was useful for high-dose areas in the later phases of the incident.

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