Purpose: Our goal was to evaluate the comparative effectiveness of robotassisted laparoscopic prostatectomy (RALP) and open radical prostatectomy (ORP) in a multicenter study. Materials and Methods: We evaluated men with localized prostate cancer at 11 high-volume academic medical centers in the United States from the PROST-QA (2003e2006) and the PROST-QA/RP2 cohorts (2010e2013) with a pre-specified goal of comparing RALP (549) and ORP (545). We measured longitudinal patient-reported health-related quality of life (HRQOL) at pre-treatment and at 2, 6, 12, and 24 months, and pathological and perioperative outcomes/complications. Results: Demographics, cancer characteristics, and margin status were similar between surgical approaches. ORP subjects were more likely to undergo lymphadenectomy (89% vs 47%; p <0.01) and nerve sparing (94% vs 89%; p <0.01).
The current study investigates the relationship between the protective factors of initiative, self-control, and attachment and their ability to predict levels of behavioral concern in a Head Start population (N=1885). Considerable research has found strong connections between protective factors and positive outcomes. However, little research has examined the unique contributions of multiple protective factors concurrently. Results of the current study indicate that when children have any one protective factor they are likely to have other protective factors. When considered individually, protective factors are predictive of low levels of behavior concern. Conversely, when all protective factors are considered together, only self-control predicts a lack of behavior concern. This implies that strength-based screeners can inform interventions that improve protective factors and may reduce behavioral problems in at-risk preschool populations.
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