The purpose of this study is to investigate the relationship between bone age, chronological age, anthropometric parameters, and diagnosed pulse rate on child-adolescence's growth according to sex and the revelation of secondary sexual characteristics. Methods: Growth-concerned 44 children and adolescence (from 6 to 16 years) were analyzed in retrospective study. They visited Korean Medical Clinic in Suwon, Korea from January 2012 to October 2013. Individual bone age (BA), chronological age (CA), Risser sign, anthropometric parameters, and pulse rate were measured. The correlations of each variable were done by Pearson analysis, Spearman analysis and Regression analysis. Results: 1. The female group was shown to have stronger negative correlation between pulse rate and BA, CA than the male group. In gender analysis, the female group showed negative correlation between weight and pulse rate. 2. In a further analysis according to the revelation of secondary sexual characteristics, the group of child-adolescent without secondary sexual characteristics was shown to have stronger negative correlation between pulse rate and BA, CA than the group with secondary sexual characteristics. The height percentile and pulse rate were negative correlation in secondary sexual character being. 3. The Risser sign and pulse rate were not correlated in this study. Conclusions: These findings suggested that a regular and continual measurement of pulse rate is effective in estimating potential for growth in child-adolescent group.
We aimed to investigate the predictive factors and optimal age for response to herbal medicine treatment for height gain in children. Methods: This retrospective chart review included 61 children (age range, 5-16 years) treated for height gain between 2011 and 2015. A predictive model was established by multiple linear regression analysis. Dependent variables were defined by the differences in percentile before and after herbal medicine treatment. The optimal cutoff value of patient age was determined by receiver operating curve analysis. Results : The age of initiation of herbal medicine therapy (p = 0.012) and administration of Forsythiae fructus (p = 0.002) were significant variables for treatment response. The adjusted R2 value was 0.231. The mean ages of the responder and non-responder groups were significantly different (p = 0.023). The optimal cutoff value of age for predicting treatment response was 9.75 years. Treatment response was better among children below 9.75 years of age. Conclusions: Patient age and administration of Forsythiae fructus were identified as determinants of response to herbal medicine treatment. Treatment of rhinitis and initiation of height gain treatment at an early age are critical for better response. These findings will provide fundamental data for further research.
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