High blood cholesterol level can cause atherosclerosis which is potentially cause coronary heart disease. Pindang patin is one of the favourite foods in Palembang which contain omega 3 fatty acids that can decrease blood cholesterol level. The aim of this study was to see the effect of pindang patin intake on total cholesterol and LDL. The type of this study was laboratory experimental using a pre-post-test randomized design with a control group in male mice (Mus musculus L.). The mice were given the high-fat diet by using egg yolk as much as 20% of body weight. The samples were divided into 5 groups: Negative Control, Positive Control, Dose I (0.26 ml/20 grams of body weight), Dose II (0.52 ml/20 grams of body weight) and Dose III (1.04 ml/20 grams of body weight). Blood samples were examined by using a spectrophotometer. Dose II and Dose III give the effect in decreasing the blood level of cholesterol in male mice, and Dose III give the effect in decreasing the blood level of LDL of male mice. Pindang patin can decrease the blood total cholesterol and LDL levels of male mice, and the best dose is in 1.04 ml/20 grams of body weight.
Abstract:Thalassemia is a genetic disease that is inherited through marriage. At present, the incidence of thalassemia can only be reduced by reducing the birth of thalassemia children. Giving a correct understanding to the community is the right way to prevent the increase in new thalassemia sufferers. This community service activity is carried out in Lubuklinggau City, South Sumatra by involving lecturers who focus on the prevention of thalassemia. Activities carried out in the form of counseling and demonstration about thalassemia to 56 participants. In this activity, the demonstration was carried out using tools such as brochures / leaflets. An evaluation of the success of the activity is carried out using random questions to the participants before and after the activity. After counseling, most participants understood the simple way to recognize and prevent thalassemia. From these community service activities, it can be concluded that counseling and demonstration, can be used to improve people's knowledge and simple skills in recognizing and preventing thalassemia. Keywords: Counseling, prevent, recognize, thalassemia Abstrak: Thalassemia merupakan penyakit genetik yang diturunkan melalui perkawinan. Saat ini, angka kejadian penyakit thalassemia hanya dapat turunkan dengan cara mengurangi kelahiran anak thalassemia. Pemberian pemahaman yang benar kepada masyarakat merupakan cara yang tepat guna mencegah peningkatan penderita thalassemia baru. Kegiatan pengabdian masyarakat ini dilakukan di Kota Lubuklinggau, Sumatera Selatan dengan melibatkan dosen yang fokus pada usaha pencegahan thalassemia. Kegiatan yang dilakukan berupa penyuluhan dan demonstrasi tentang thalassemia terhadap 56 orang peserta. Dalam kegiatan ini, demontrasi dilakukan dengan menggunakan alat bantu berupa brosur/leaflet. Evaluasi terhadap keberhasilan kegiatan dilakukan dengan menggunakan pertanyaan acak kepada peserta sebelum dan sesudah kegiatan. Setelah penyuluhan, sebagian besar peserta memahami cara sederhana mengenali dan mencegah thalassemia. Dari kegiatan pengabdian masyarakat ini, dapat simpulkan bahwa penyuluhan dan demonstrasi, dapat digunakan untuk meningkatkan pengetahuan dan keterampilan sederhana masyarakat dalam mengenali dan mencegah thalassemia. MIOS. Kata Kunci: Mencegah, mengenali, penyuluhan, thalassemia
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