The diagnosis of dilated cardiomyopathy (DCM) remains a challenge in clinical radiology. This study aimed to investigate whether texture analysis (TA) parameters on magnetic resonance T1 mapping can be helpful for the diagnosis of DCM.A total of 50 DCM cases were retrospectively screened and 24 healthy controls were prospectively recruited between March 2015 and July 2017. T1 maps were acquired using the Modified Look-Locker Inversion Recovery (MOLLI) sequence at a 3.0 T MR scanner. The endocardium and epicardium were drawn on the short-axis slices of the T1 maps by an experienced radiologist. Twelve histogram parameters and 5 gray-level co-occurrence matrix (GLCM) features were extracted during the TA. Differences in texture features between DCM patients and healthy controls were evaluated by t test. Support vector machine (SVM) was used to calculate the diagnostic accuracy of those texture parameters.Most histogram features were higher in the DCM group when compared to healthy controls, and 9 of these had significant differences between the DCM group and healthy controls. In terms of GLCM features, energy, correlation, and homogeneity were higher in the DCM group, when compared with healthy controls. In addition, entropy and contrast were lower in the DCM group. Moreover, entropy, contrast, and homogeneity had significant differences between these 2 groups. The diagnostic accuracy when using the SVM classifier with all these histogram and GLCM features was 0.85 ± 0.07.A computer-based TA and machine learning approach of T1 mapping can provide an objective tool for the diagnosis of DCM.

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Salient object segmentation aims at distinguishing various salient objects from backgrounds. Despite the lack of semantic consistency, salient objects often have obvious texture and location characteristics in local area. Based on this priori, we propose a novel Local Context Attention Network (LCANet) to generate locally reinforcement feature maps in a uniform representational architecture. The proposed network introduces an Attentional Correlation Filter (ACF) module to generate explicit local attention by calculating the correlation feature map between coarse prediction and global context. Then it is expanded to a Local Context Block(LCB). Furthermore, an one-stage coarse-tofine structure is implemented based on LCB to adaptively enhance the local context description ability. Comprehensive experiments are conducted on several salient object segmentation datasets, demonstrating the superior performance of the proposed LCANet against the state-ofthe-art methods, especially with 0.883 max F-score and 0.034 MAE on DUTS-TE dataset.

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