Electrochemical reduction via paired electrolysis has been used to achieve deoxygenative reduction of ketones. As a result of the complexing of ketones with the triphenylphosphine radical cation generated by anodic...

An external oxidant‐free protocol for the generation of isocyanates from hydroxamic acids assisted by trivalent phosphine under mild electrochemical conditions was reported. The process started with the anodic oxidation of hydroxamic acids, followed by reacting with phosphine to form corresponding alkoxyphosphoniums and subsequent rearrangement with the release of tri‐substituted phosphine oxide as the driving force to give isocyanates, which were trapped by N‐based nucleophiles to produce various ureas. This method provides a broadly applicable procedure to access isocyanate intermediates under mild electrochemical conditions.

Herein, N2-selective β-thioalkylation of benzotriazoles with unactivated alkenes and styrenes is reported. The N2-selective β-thioalkylation of benzotriazoles is highly stereospecific and works under simple and mild conditions, exhibiting excellent functional group tolerance. The high N2-selectivity is a consequence of the combination of hydrogen bonding and Lewis acid/base activation, which reverses the N2-position to be favored for alkylation.

The construction of diaryl alkanes from aromatic aldehydes or ketones with electron-deficient arenes is achieved in the presence of trivalent phosphine under electrochemical conditions. A reductive coupling between electron-deficient arenes...

Silicon phthalocyanine derivatives 1a and 1b were synthesized and characterized by UV, 1 H-NMR and MS. The photophysical properties of the compounds in DMSO were investigated. The maximum absorption peaks of compounds 1a and 1b at the Q-band are 681 nm. With ZnPc (Φ F = 0.20, Φ Δ = 0.67) as a reference, the fluorescence quantum yield (Φ F ) of 1a and 1b are 0.20 and 0.31 respectively, and the singlet oxygen quantum yield (Φ Δ ) are 0.66 and 0.59 respectively. The DNA-photocleavage activities of compounds 1a and 1b were studied by gel electrophoresis. Compounds 1a and 1b possess good photocleavage activity to pBR322 DNA. The results demonstrate that compounds 1a and 1b are potential photosensitizers for tumor therapy.